Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:5336
  • Symbol:PLCG2
  • Description:phospholipase C gamma 2

Function

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5336 GO:0001784 IPI enables phosphotyrosine residue binding 20624904 Function
5336 GO:0004435 IDA enables phosphatidylinositol phospholipase C activity 11606584,12181444 Function
5336 GO:0004435 IMP enables phosphatidylinositol phospholipase C activity 32514138 Function
5336 GO:0005515 IPI enables protein binding 15644415,16273093,24642916,24658140,24728074,25241761,25814554..... Function
5336 GO:0019901 IPI enables protein kinase binding 11606584,14656219 Function
5336 GO:0097110 IPI enables scaffold protein binding 11606584,23555801 Function
5336 GO:1990782 IPI enables protein tyrosine kinase binding 32514138 Function

Component

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5336 GO:0005737 IDA located_in cytoplasm 11331309 Component
5336 GO:0005886 IDA is_active_in plasma membrane 11331309,11606584 Component
5336 GO:0005886 IDA located_in plasma membrane 11606584 Component
5336 GO:0032587 IDA is_active_in ruffle membrane 11331309 Component
5336 GO:0048471 IDA located_in perinuclear region of cytoplasm 23555801 Component
5336 GO:0070062 HDA located_in extracellular exosome 20458337 Component
5336 GO:0097708 IDA located_in intracellular vesicle 11331309 Component

Process

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5336 GO:0006661 IDA involved_in phosphatidylinositol biosynthetic process 11606584,12181444 Process
5336 GO:0010628 IMP acts_upstream_of_or_within positive regulation of gene expression 32514138 Process
5336 GO:0019216 IMP acts_upstream_of regulation of lipid metabolic process 32514138 Process
5336 GO:0019722 IMP involved_in calcium-mediated signaling 11606584 Process
5336 GO:0031663 IMP involved_in lipopolysaccharide-mediated signaling pathway 32514138 Process
5336 GO:0035556 IDA involved_in intracellular signal transduction 11606584,14656219 Process
5336 GO:0035556 IMP involved_in intracellular signal transduction 32514138 Process
5336 GO:0048678 IMP involved_in response to axon injury 32514138 Process
5336 GO:0050853 IDA involved_in B cell receptor signaling pathway 15509800 Process
5336 GO:0050853 IMP involved_in B cell receptor signaling pathway 11606584 Process
5336 GO:0051209 IDA involved_in release of sequestered calcium ion into cytosol 11606584 Process
5336 GO:0060100 IMP acts_upstream_of_or_within positive regulation of phagocytosis, engulfment 32514138 Process
5336 GO:0071277 IMP involved_in cellular response to calcium ion 11606584 Process
5336 GO:0071396 IMP involved_in cellular response to lipid 32514138 Process
5336 GO:0150078 IMP involved_in positive regulation of neuroinflammatory response 32514138 Process
5336 GO:1900227 IMP acts_upstream_of_or_within positive regulation of NLRP3 inflammasome complex assembly 32514138 Process