Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:53373
  • Symbol:TPCN1
  • Description:two pore segment channel 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
53373 GO:0005248 IDA enables voltage-gated sodium channel activity 24776928 Function
53373 GO:0005515 IPI enables protein binding 15094197,21903581,24188827 Function
53373 GO:0015280 IDA enables ligand-gated sodium channel activity 23063126,24776928 Function
53373 GO:0042802 IPI enables identical protein binding 21903581 Function
53373 GO:0072345 IDA NOT enables NAADP-sensitive calcium-release channel activity 24776928 Function
53373 GO:0072345 IDA enables NAADP-sensitive calcium-release channel activity 19620632 Function
53373 GO:0097682 IDA enables intracellular phosphatidylinositol-3,5-bisphosphate-sensitive monatomic cation channel activity 23063126,24776928 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
53373 GO:0005765 IDA located_in lysosomal membrane 19620632,23063126 Component
53373 GO:0010008 IDA located_in endosome membrane 19620632,23063126 Component
53373 GO:0036019 IDA located_in endolysosome 24776928 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
53373 GO:0010508 IDA involved_in positive regulation of autophagy 22012985 Process
53373 GO:0075509 IMP involved_in endocytosis involved in viral entry into host cell 25722412 Process