Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:538
  • Symbol:ATP7A
  • Description:ATPase copper transporting alpha

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
538 GO:0005507 IDA enables copper ion binding 15670166 Function
538 GO:0005515 IPI enables protein binding 16051599,16371425,16884690,21667063,23563491,26199316..... Function
538 GO:0005524 IDA enables ATP binding 19917612 Function
538 GO:0032767 IDA enables copper-dependent protein binding 31283225 Function
538 GO:0032767 IPI enables copper-dependent protein binding 10497213 Function
538 GO:0140581 IDA enables P-type monovalent copper transporter activity 10419525 Function
538 GO:1903136 IDA enables cuprous ion binding 31283225 Function
538 GO:1903136 IMP enables cuprous ion binding 14572476,15035611 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
538 GO:0005770 IDA located_in late endosome 8943055 Component
538 GO:0005794 IDA located_in Golgi apparatus 9467005 Component
538 GO:0005802 IDA located_in trans-Golgi network 8943055,12812980 Component
538 GO:0005886 IDA located_in plasma membrane 12812980 Component
538 GO:0016020 HDA located_in membrane 19946888 Component
538 GO:0016323 IDA located_in basolateral plasma membrane 16397091 Component
538 GO:0030140 IMP located_in trans-Golgi network transport vesicle 9817923 Component
538 GO:0048471 IDA located_in perinuclear region of cytoplasm 8943055,10567439,16397091 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
538 GO:0006825 IMP involved_in copper ion transport 11092760 Process
538 GO:0006878 IMP involved_in intracellular copper ion homeostasis 16397091,28389643 Process
538 GO:0032773 IMP involved_in positive regulation of tyrosinase activity 11092760 Process
538 GO:0048023 IMP involved_in positive regulation of melanin biosynthetic process 11092760 Process
538 GO:0060003 IDA involved_in copper ion export 10419525 Process