Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:540
• Symbol:ATP7B
• Description:ATPase copper transporting beta

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
540	GO:0005375	IDA	enables	copper ion transmembrane transporter activity	26004889	Function
540	GO:0005507	IDA	enables	copper ion binding	12029094,14709553	Function
540	GO:0005515	IPI	enables	protein binding	12968035,16554302,16676348,16884690,17919502	Function
540	GO:0005524	IDA	enables	ATP binding	15205462,16567646	Function
540	GO:0043682	IMP	enables	P-type divalent copper transporter activity	9837819	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
540	GO:0005770	IDA	located_in	late endosome	15681833	Component
540	GO:0005794	IDA	located_in	Golgi apparatus		Component
540	GO:0005802	IDA	colocalizes_with	trans-Golgi network	15269005,16472602	Component
540	GO:0016020	HDA	located_in	membrane	19946888	Component
540	GO:0016323	IDA	colocalizes_with	basolateral plasma membrane	15269005	Component
540	GO:0031410	IDA	colocalizes_with	cytoplasmic vesicle	16472602	Component
540	GO:0032588	IDA	located_in	trans-Golgi network membrane	9837819	Component
540	GO:0048471	IDA	colocalizes_with	perinuclear region of cytoplasm	16939419	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
540	GO:0006825	IDA	involved_in	copper ion transport	26004889	Process
540	GO:0006825	IGI	involved_in	copper ion transport	12572677,26004889	Process
540	GO:0006825	IMP	involved_in	copper ion transport	9837819	Process
540	GO:0015677	IDA	involved_in	copper ion import	16472602	Process
540	GO:0046688	IDA	involved_in	response to copper ion	15269005,16472602,16939419	Process
540	GO:0051208	IDA	involved_in	sequestering of calcium ion	16472602	Process