Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:545
  • Symbol:ATR
  • Description:ATR serine/threonine kinase

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
545 GO:0000077 IDA involved_in DNA damage checkpoint signaling 14657349 Process
545 GO:0006974 IDA involved_in DNA damage response 27723717,27723720 Process
545 GO:0008156 IMP involved_in negative regulation of DNA replication 14657349 Process
545 GO:0018105 IDA involved_in peptidyl-serine phosphorylation 9733515 Process
545 GO:0034644 IMP involved_in cellular response to UV 9925639 Process
545 GO:0043517 IMP involved_in positive regulation of DNA damage response, signal transduction by p53 class mediator 9925639 Process
545 GO:0046777 IDA involved_in protein autophosphorylation 9733515 Process
545 GO:0070198 IMP involved_in protein localization to chromosome, telomeric region 21829167 Process
545 GO:0071480 IDA involved_in cellular response to gamma radiation 9925639 Process
545 GO:0090399 IMP involved_in replicative senescence 15149599 Process
545 GO:0097694 IMP involved_in establishment of RNA localization to telomere 26586433 Process
545 GO:1904884 IMP involved_in positive regulation of telomerase catalytic core complex assembly 26586433 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
545 GO:0004672 IDA enables protein kinase activity 14657349 Function
545 GO:0004674 IDA enables protein serine/threonine kinase activity 9733515,9925639,27723717,27723720 Function
545 GO:0005515 IPI enables protein binding 9733515,14657349,17686975,18583959,19633697,19889979,20616048,..... Function
545 GO:0032405 IDA enables MutLalpha complex binding 16713580 Function
545 GO:0032407 IDA enables MutSalpha complex binding 16713580 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
545 GO:0005654 IDA located_in nucleoplasm Component
545 GO:0005794 IDA located_in Golgi apparatus Component
545 GO:0016605 IDA located_in PML body 12814551 Component
545 GO:0070310 IPI part_of ATR-ATRIP complex 11721054 Component