Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:5566
  • Symbol:PRKACA
  • Description:protein kinase cAMP-activated catalytic subunit alpha

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5566 GO:0004672 IDA enables protein kinase activity 12475942 Function
5566 GO:0004674 IDA enables protein serine/threonine kinase activity 21085490 Function
5566 GO:0004674 IMP enables protein serine/threonine kinase activity 26537248 Function
5566 GO:0004691 IDA enables cAMP-dependent protein kinase activity 11029056 Function
5566 GO:0004712 IDA enables protein serine/threonine/tyrosine kinase activity 22797923 Function
5566 GO:0005515 IPI enables protein binding 11035810,12475942,15630084,15655353,16387847,17148597,17911601..... Function
5566 GO:0019901 IPI enables protein kinase binding 11035810,17911601 Function
5566 GO:0031625 IDA enables ubiquitin protein ligase binding 21423175 Function
5566 GO:0034237 IPI enables protein kinase A regulatory subunit binding 17911601 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5566 GO:0005634 HDA located_in nucleus 21630459 Component
5566 GO:0005634 IDA located_in nucleus 21085490 Component
5566 GO:0005737 IDA located_in cytoplasm 21085490 Component
5566 GO:0005813 IDA located_in centrosome 21399614 Component
5566 GO:0005886 IDA located_in plasma membrane 15569306 Component
5566 GO:0005930 IDA colocalizes_with axoneme 12475942 Component
5566 GO:0005952 IDA part_of cAMP-dependent protein kinase complex 12475942 Component
5566 GO:0016607 IDA located_in nuclear speck 17594903 Component
5566 GO:0044853 IDA located_in plasma membrane raft 17911601 Component
5566 GO:0048471 IDA located_in perinuclear region of cytoplasm 21085490 Component
5566 GO:0070062 HDA located_in extracellular exosome 23533145 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5566 GO:0006397 IDA involved_in mRNA processing 17594903 Process
5566 GO:0006468 IDA involved_in protein phosphorylation 12475942 Process
5566 GO:0018105 IDA involved_in peptidyl-serine phosphorylation 10805756,11029056 Process
5566 GO:0018105 IMP involved_in peptidyl-serine phosphorylation 26537248 Process
5566 GO:0034605 IDA involved_in cellular response to heat 21085490 Process
5566 GO:0045667 IDA involved_in regulation of osteoblast differentiation 19949837 Process
5566 GO:0061136 IDA involved_in regulation of proteasomal protein catabolic process 17565987 Process
5566 GO:0071333 IDA involved_in cellular response to glucose stimulus 19949837 Process
5566 GO:2000810 IDA involved_in regulation of bicellular tight junction assembly 15905176 Process