Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5576
• Symbol:PRKAR2A
• Description:protein kinase cAMP-dependent type II regulatory subunit alpha

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
5576	GO:0004862	IDA	enables	cAMP-dependent protein kinase inhibitor activity	21812984	Function
5576	GO:0005515	IPI	enables	protein binding	9473338,11278869,11414803,12475942,16642035,17911601,20007971,.....	Function
5576	GO:0008603	IDA	enables	cAMP-dependent protein kinase regulator activity	21812984	Function
5576	GO:0019904	IPI	enables	protein domain specific binding	25097019	Function
5576	GO:0031625	IDA	enables	ubiquitin protein ligase binding	21423175	Function
5576	GO:0034236	IPI	enables	protein kinase A catalytic subunit binding	17911601,21812984	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
5576	GO:0005737	IDA	located_in	cytoplasm	21423175	Component
5576	GO:0005813	IDA	located_in	centrosome	21399614	Component
5576	GO:0005886	IDA	located_in	plasma membrane	21423175	Component
5576	GO:0005925	HDA	located_in	focal adhesion	21423176	Component
5576	GO:0005930	IDA	colocalizes_with	axoneme	12475942	Component
5576	GO:0005952	IDA	part_of	cAMP-dependent protein kinase complex	12475942	Component
5576	GO:0016020	HDA	located_in	membrane	19946888	Component
5576	GO:0031588	IDA	part_of	nucleotide-activated protein kinase complex	21812984	Component
5576	GO:0032991	IDA	part_of	protein-containing complex	25097019	Component
5576	GO:0044853	IDA	located_in	plasma membrane raft	17911601	Component
5576	GO:0070062	HDA	located_in	extracellular exosome	19056867,20458337,23533145	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
5576	GO:2000480	IDA	involved_in	negative regulation of cAMP-dependent protein kinase activity	21812984	Process