Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:5594
  • Symbol:MAPK1
  • Description:mitogen-activated protein kinase 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5594 GO:0004674 IDA enables protein serine/threonine kinase activity 7588608,15850461,18794356,22031296,26996940 Function
5594 GO:0005515 IPI enables protein binding 9632734,10415025,10601328,11489891,12592337,12840032,15133037,..... Function
5594 GO:0019902 IPI enables phosphatase binding 19494114 Function
5594 GO:0042802 IPI enables identical protein binding 16627622,26267534 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5594 GO:0005634 HDA located_in nucleus 16791210 Component
5594 GO:0005634 IDA located_in nucleus 18794356,32721402 Component
5594 GO:0005737 HDA located_in cytoplasm 16791210 Component
5594 GO:0005737 IDA located_in cytoplasm 18794356,32721402 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5594 GO:0006468 IDA involved_in protein phosphorylation 23184662 Process
5594 GO:0010759 IGI acts_upstream_of positive regulation of macrophage chemotaxis 26754294 Process
5594 GO:0010800 IDA involved_in positive regulation of peptidyl-threonine phosphorylation 16314496 Process
5594 GO:0018105 IDA involved_in peptidyl-serine phosphorylation 15850461 Process
5594 GO:0030521 IMP involved_in androgen receptor signaling pathway 22031296 Process
5594 GO:0032212 IMP involved_in positive regulation of telomere maintenance via telomerase 21531765 Process
5594 GO:0034198 IDA involved_in cellular response to amino acid starvation 11096076 Process
5594 GO:0034614 IMP involved_in cellular response to reactive oxygen species 26514923 Process
5594 GO:0038127 IDA involved_in ERBB signaling pathway 15133037 Process
5594 GO:0043401 IMP involved_in steroid hormone mediated signaling pathway 22031296 Process
5594 GO:0050847 IMP involved_in progesterone receptor signaling pathway 22031296 Process
5594 GO:0051403 IDA involved_in stress-activated MAPK cascade 11096076 Process
5594 GO:0051973 IMP involved_in positive regulation of telomerase activity 21531765 Process
5594 GO:0070371 IDA involved_in ERK1 and ERK2 cascade 16314496,22031296 Process
5594 GO:0070849 IDA involved_in response to epidermal growth factor 18794356 Process
5594 GO:0071276 IMP involved_in cellular response to cadmium ion 26514923 Process
5594 GO:0120041 IGI acts_upstream_of positive regulation of macrophage proliferation 26754294 Process
5594 GO:1904355 IMP involved_in positive regulation of telomere capping 21531765 Process