Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:5604
  • Symbol:MAP2K1
  • Description:mitogen-activated protein kinase kinase 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5604 GO:0004708 IDA enables MAP kinase kinase activity 8388392,28166211 Function
5604 GO:0005078 IMP enables MAP-kinase scaffold activity 29433126 Function
5604 GO:0005515 IDA enables protein binding 22572157 Function
5604 GO:0005515 IPI enables protein binding 15299019,17110930,17255949,17724343,17979178,18329369,19197339..... Function
5604 GO:0030295 IDA enables protein kinase activator activity 10644344 Function
5604 GO:0043539 IDA enables protein serine/threonine kinase activator activity 8388392 Function
5604 GO:0097110 IPI enables scaffold protein binding 10409742 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5604 GO:0005783 IDA located_in endoplasmic reticulum 22572157 Component
5604 GO:0005829 IDA located_in cytosol Component
5604 GO:0005886 IDA located_in plasma membrane Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5604 GO:0006468 IDA involved_in protein phosphorylation 28166211 Process
5604 GO:0008285 IDA involved_in negative regulation of cell population proliferation 9765203 Process
5604 GO:0010628 IMP involved_in positive regulation of gene expression 15155804,24375836 Process
5604 GO:0045893 IMP involved_in positive regulation of DNA-templated transcription 24375836,26514923 Process
5604 GO:0070374 IMP involved_in positive regulation of ERK1 and ERK2 cascade 24375836 Process
5604 GO:0071902 IDA involved_in positive regulation of protein serine/threonine kinase activity 8388392 Process
5604 GO:0090398 IMP involved_in cellular senescence 9765203 Process