Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5605
• Symbol:MAP2K2
• Description:mitogen-activated protein kinase kinase 2

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
5605	GO:0004708	IDA	enables	MAP kinase kinase activity	8388392	Function
5605	GO:0005078	IMP	enables	MAP-kinase scaffold activity	29433126	Function
5605	GO:0005515	IPI	enables	protein binding	11909642,17979178,21615688,21988832,24746704,25416956,25600339.....	Function
5605	GO:0030165	IDA	enables	PDZ domain binding	21615688	Function
5605	GO:0043539	IDA	enables	protein serine/threonine kinase activator activity	8388392	Function
5605	GO:0097110	IPI	enables	scaffold protein binding	10409742,21615688	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
5605	GO:0005778	HDA	located_in	peroxisomal membrane	21525035	Component
5605	GO:0005783	IDA	located_in	endoplasmic reticulum	21615688	Component
5605	GO:0005794	IDA	located_in	Golgi apparatus	21615688	Component
5605	GO:0005874	IDA	located_in	microtubule	21615688	Component
5605	GO:0005911	IDA	located_in	cell-cell junction	21615688	Component
5605	GO:0009898	IDA	located_in	cytoplasmic side of plasma membrane	21615688	Component
5605	GO:0048471	IDA	located_in	perinuclear region of cytoplasm	21615688	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
5605	GO:0010628	IMP	involved_in	positive regulation of gene expression	24375836	Process
5605	GO:0036289	IDA	involved_in	peptidyl-serine autophosphorylation	8388392	Process
5605	GO:0045893	IMP	involved_in	positive regulation of DNA-templated transcription	24375836	Process
5605	GO:0070371	IMP	involved_in	ERK1 and ERK2 cascade	24375836	Process
5605	GO:0071902	IDA	involved_in	positive regulation of protein serine/threonine kinase activity	8388392	Process