Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:5610
  • Symbol:EIF2AK2
  • Description:eukaryotic translation initiation factor 2 alpha kinase 2

Function

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5610 GO:0003723 HDA enables RNA binding 22681889 Function
5610 GO:0003725 IDA enables double-stranded RNA binding 21266579 Function
5610 GO:0004672 IDA enables protein kinase activity 12882984,15229216,18835251 Function
5610 GO:0004672 IMP enables protein kinase activity 21123651 Function
5610 GO:0004694 IMP enables eukaryotic translation initiation factor 2alpha kinase activity 25329545 Function
5610 GO:0005515 IPI enables protein binding 8576172,9143277,9431994,10390359,10488152,11160738,11773402,11..... Function
5610 GO:0016301 IDA enables kinase activity 21123651 Function
5610 GO:0042802 IPI enables identical protein binding 16373505 Function

Component

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5610 GO:0005737 IDA is_active_in cytoplasm 21123651 Component
5610 GO:0005737 IDA located_in cytoplasm 15121867 Component
5610 GO:0005829 IDA located_in cytosol Component
5610 GO:0016020 HDA located_in membrane 19946888 Component
5610 GO:0048471 IDA located_in perinuclear region of cytoplasm 15121867 Component

Process

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5610 GO:0006468 IDA involved_in protein phosphorylation 19189853 Process
5610 GO:0009615 IMP involved_in response to virus 19189853 Process
5610 GO:0017148 IDA involved_in negative regulation of translation 12882984 Process
5610 GO:0017148 IMP involved_in negative regulation of translation 12610133,19189853 Process
5610 GO:0033689 IMP involved_in negative regulation of osteoblast proliferation 16216244 Process
5610 GO:0034198 IMP involved_in cellular response to amino acid starvation 25329545 Process
5610 GO:0035455 IDA involved_in response to interferon-alpha 19840259 Process
5610 GO:0043410 IMP involved_in positive regulation of MAPK cascade 15229216 Process
5610 GO:0045071 IMP involved_in negative regulation of viral genome replication 19189853,19840259 Process
5610 GO:0046777 IDA involved_in protein autophosphorylation 22801494 Process
5610 GO:0046777 IMP involved_in protein autophosphorylation 16216244 Process
5610 GO:0051092 IDA involved_in positive regulation of NF-kappaB transcription factor activity 15121867 Process
5610 GO:0051607 IEP involved_in defense response to virus 32634389 Process
5610 GO:0140374 IDA involved_in antiviral innate immune response 21145228 Process