Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:56637
  • Symbol:Gsk3b
  • Description:glycogen synthase kinase 3 beta

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
56637 GO:0000320 IDA acts_upstream_of_or_within re-entry into mitotic cell cycle 12502791 Process
56637 GO:0001558 IMP acts_upstream_of_or_within regulation of cell growth 18824542 Process
56637 GO:0006349 IMP involved_in regulation of gene expression by genomic imprinting 21047779 Process
56637 GO:0006366 IMP acts_upstream_of transcription by RNA polymerase II 23015435 Process
56637 GO:0006468 IDA acts_upstream_of_or_within protein phosphorylation 12432063,12805290,14730361,17026964 Process
56637 GO:0006468 IGI acts_upstream_of_or_within protein phosphorylation 19141611 Process
56637 GO:0006468 IMP involved_in protein phosphorylation 16543145 Process
56637 GO:0006611 IDA acts_upstream_of_or_within protein export from nucleus 11782539 Process
56637 GO:0006983 IDA acts_upstream_of_or_within ER overload response 14744935 Process
56637 GO:0007127 IMP involved_in meiosis I 29228573 Process
56637 GO:0007409 IGI acts_upstream_of_or_within axonogenesis 18716223 Process
56637 GO:0007520 IDA acts_upstream_of_or_within myoblast fusion 15282335 Process
56637 GO:0007520 IGI acts_upstream_of_or_within myoblast fusion 15282335 Process
56637 GO:0007623 IMP involved_in circadian rhythm 20123978 Process
56637 GO:0008286 IDA involved_in insulin receptor signaling pathway 28057765 Process
56637 GO:0009887 IMP acts_upstream_of_or_within animal organ morphogenesis 10894547 Process
56637 GO:0010508 IDA involved_in positive regulation of autophagy 22539723 Process
56637 GO:0010508 IGI involved_in positive regulation of autophagy 26160071 Process
56637 GO:0010614 IDA acts_upstream_of_or_within negative regulation of cardiac muscle hypertrophy 11782539 Process
56637 GO:0010628 IGI involved_in positive regulation of gene expression 20371704 Process
56637 GO:0010628 IMP involved_in positive regulation of gene expression 24974728 Process
56637 GO:0010800 IDA acts_upstream_of_or_within positive regulation of peptidyl-threonine phosphorylation 17986005 Process
56637 GO:0010975 IGI acts_upstream_of_or_within regulation of neuron projection development 24227739 Process
56637 GO:0010977 IGI acts_upstream_of_or_within negative regulation of neuron projection development 23015435 Process
56637 GO:0010977 IMP acts_upstream_of_or_within negative regulation of neuron projection development 23015435 Process
56637 GO:0014043 IGI acts_upstream_of_or_within negative regulation of neuron maturation 23015435 Process
56637 GO:0014902 IGI acts_upstream_of_or_within myotube differentiation 15282335 Process
56637 GO:0016055 IGI acts_upstream_of_or_within Wnt signaling pathway 23074275 Process
56637 GO:0016310 IMP involved_in phosphorylation 17182001 Process
56637 GO:0016477 IGI acts_upstream_of_or_within cell migration 17986005 Process
56637 GO:0018105 IDA acts_upstream_of_or_within peptidyl-serine phosphorylation 17986005 Process
56637 GO:0018105 IDA involved_in peptidyl-serine phosphorylation 20123978 Process
56637 GO:0018105 IGI involved_in peptidyl-serine phosphorylation 16537926 Process
56637 GO:0032007 IGI involved_in negative regulation of TOR signaling 26160071 Process
56637 GO:0032092 IDA acts_upstream_of_or_within positive regulation of protein binding 19141611 Process
56637 GO:0032436 IGI acts_upstream_of_or_within positive regulation of proteasomal ubiquitin-dependent protein catabolic process 22660580 Process
56637 GO:0032886 IDA involved_in regulation of microtubule-based process 21295697 Process
56637 GO:0035372 IGI acts_upstream_of_or_within protein localization to microtubule 18716223 Process
56637 GO:0035729 IDA acts_upstream_of_or_within cellular response to hepatocyte growth factor stimulus 21072211 Process
56637 GO:0036016 IDA involved_in cellular response to interleukin-3 16543145 Process
56637 GO:0042752 IMP involved_in regulation of circadian rhythm 28556462 Process
56637 GO:0042981 IMP involved_in regulation of apoptotic process 12154096 Process
56637 GO:0043066 IMP acts_upstream_of_or_within negative regulation of apoptotic process 10894547 Process
56637 GO:0043491 IMP involved_in protein kinase B signaling 29228573 Process
56637 GO:0044027 IMP involved_in negative regulation of gene expression via CpG island methylation 21047779 Process
56637 GO:0045444 IDA acts_upstream_of_or_within fat cell differentiation 12502791 Process
56637 GO:0045724 IMP involved_in positive regulation of cilium assembly 25860027 Process
56637 GO:0045773 IGI acts_upstream_of_or_within positive regulation of axon extension 24623780 Process
56637 GO:0045944 IMP acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 23015435 Process
56637 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 21047779 Process
56637 GO:0048675 IGI acts_upstream_of axon extension 24623780 Process
56637 GO:0048863 IMP acts_upstream_of stem cell differentiation 22064483 Process
56637 GO:0060070 IDA acts_upstream_of_or_within canonical Wnt signaling pathway 15282335 Process
56637 GO:0060070 IGI acts_upstream_of_or_within canonical Wnt signaling pathway 16815997 Process
56637 GO:0070059 IDA involved_in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 23028846 Process
56637 GO:0071385 IGI involved_in cellular response to glucocorticoid stimulus 20371704 Process
56637 GO:0090090 IMP involved_in negative regulation of canonical Wnt signaling pathway 12154096 Process
56637 GO:0097191 IGI involved_in extrinsic apoptotic signaling pathway 20371704 Process
56637 GO:0097192 IDA involved_in extrinsic apoptotic signaling pathway in absence of ligand 16543145 Process
56637 GO:1900271 IMP involved_in regulation of long-term synaptic potentiation 28556462 Process
56637 GO:1901030 IDA involved_in positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 16543145 Process
56637 GO:1903566 IMP involved_in positive regulation of protein localization to cilium 25860027 Process
56637 GO:1904780 IMP involved_in negative regulation of protein localization to centrosome 28057765 Process
56637 GO:2000727 IMP involved_in positive regulation of cardiac muscle cell differentiation 24974728 Process
56637 GO:2000738 IMP acts_upstream_of_or_within positive regulation of stem cell differentiation 22064483 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
56637 GO:0004672 IDA enables protein kinase activity 14730361,22539723 Function
56637 GO:0004674 IDA enables protein serine/threonine kinase activity 12805290,17986005,20123978,22057101,22660580,23542741,26240334..... Function
56637 GO:0004674 IMP enables protein serine/threonine kinase activity 16543145,24623780 Function
56637 GO:0005515 IPI enables protein binding 9554852,12432063,12805290,16051150,16959610,17182001,18632848,..... Function
56637 GO:0008013 IPI enables beta-catenin binding 12874278 Function
56637 GO:0019901 IPI enables protein kinase binding 22899650 Function
56637 GO:0050321 IDA enables tau-protein kinase activity 15192701 Function
56637 GO:0070840 IPI enables dynein complex binding 28057765 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
56637 GO:0005634 IDA located_in nucleus 12502791,22064483 Component
56637 GO:0005829 IDA located_in cytosol 12502791 Component
56637 GO:0014069 IDA is_active_in postsynaptic density 20111716 Component
56637 GO:0014069 IDA located_in postsynaptic density 17114649 Component
56637 GO:0030426 IDA located_in growth cone 12805290 Component
56637 GO:0030877 IDA part_of beta-catenin destruction complex 10318824 Component
56637 GO:0043025 IDA located_in neuronal cell body 12805290,23015435 Component
56637 GO:0043198 IDA located_in dendritic shaft 12805290 Component
56637 GO:0043227 IDA located_in membrane-bounded organelle 12805290 Component
56637 GO:0048471 IDA located_in perinuclear region of cytoplasm 20890042 Component
56637 GO:0072687 IDA is_active_in meiotic spindle 29228573 Component
56637 GO:0098978 IDA is_active_in glutamatergic synapse 20111716 Component
56637 GO:1990904 IDA part_of ribonucleoprotein complex 21709260 Component
56637 GO:1990909 IDA part_of Wnt signalosome 22899650 Component