Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:56717
  • Symbol:Mtor
  • Description:mechanistic target of rapamycin kinase

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
56717 GO:0001932 IDA acts_upstream_of_or_within regulation of protein phosphorylation 17556672 Process
56717 GO:0001934 IMP acts_upstream_of_or_within positive regulation of protein phosphorylation 25139234 Process
56717 GO:0002296 IMP involved_in T-helper 1 cell lineage commitment 26410627 Process
56717 GO:0003007 IMP acts_upstream_of_or_within heart morphogenesis 25139234 Process
56717 GO:0003179 IMP acts_upstream_of_or_within heart valve morphogenesis 25139234 Process
56717 GO:0006112 IMP acts_upstream_of_or_within energy reserve metabolic process 25139234 Process
56717 GO:0006207 IDA involved_in 'de novo' pyrimidine nucleobase biosynthetic process 23429704 Process
56717 GO:0006954 IGI involved_in inflammatory response 31874168 Process
56717 GO:0007281 IDA acts_upstream_of_or_within germ cell development 12140361 Process
56717 GO:0009408 IGI involved_in response to heat 31874168 Process
56717 GO:0009791 IMP acts_upstream_of_or_within post-embryonic development 25139234 Process
56717 GO:0010506 IDA involved_in regulation of autophagy 24011591 Process
56717 GO:0010507 IMP involved_in negative regulation of autophagy 21258367 Process
56717 GO:0010592 IDA acts_upstream_of_or_within positive regulation of lamellipodium assembly 15467718 Process
56717 GO:0010831 IGI acts_upstream_of_or_within positive regulation of myotube differentiation 19704009 Process
56717 GO:0016236 IMP acts_upstream_of macroautophagy 16714284 Process
56717 GO:0016242 IMP acts_upstream_of_or_within negative regulation of macroautophagy 16714284,23274896 Process
56717 GO:0018105 IDA involved_in peptidyl-serine phosphorylation 24011591 Process
56717 GO:0018105 IMP acts_upstream_of_or_within peptidyl-serine phosphorylation 18347059 Process
56717 GO:0018107 IDA acts_upstream_of_or_within peptidyl-threonine phosphorylation 11707573 Process
56717 GO:0019228 IGI involved_in neuronal action potential 31874168 Process
56717 GO:0030030 IMP acts_upstream_of_or_within cell projection organization 16286931 Process
56717 GO:0030838 IDA acts_upstream_of_or_within positive regulation of actin filament polymerization 15467718 Process
56717 GO:0030838 IMP acts_upstream_of_or_within positive regulation of actin filament polymerization 15467718 Process
56717 GO:0031529 IDA acts_upstream_of_or_within ruffle organization 15467718 Process
56717 GO:0031641 IMP acts_upstream_of_or_within regulation of myelination 24101522 Process
56717 GO:0031669 IDA involved_in cellular response to nutrient levels 21258367 Process
56717 GO:0031929 IGI involved_in TOR signaling 26160071 Process
56717 GO:0032868 IDA acts_upstream_of_or_within response to insulin 15467718 Process
56717 GO:0033173 IMP acts_upstream_of calcineurin-NFAT signaling cascade 18347059 Process
56717 GO:0035264 IMP acts_upstream_of_or_within multicellular organism growth 25139234 Process
56717 GO:0042752 IMP involved_in regulation of circadian rhythm 29750810 Process
56717 GO:0043087 IMP acts_upstream_of_or_within regulation of GTPase activity 15467718 Process
56717 GO:0043200 IDA acts_upstream_of_or_within response to amino acid 15467718 Process
56717 GO:0045670 IDA involved_in regulation of osteoclast differentiation 19440205 Process
56717 GO:0045792 IGI acts_upstream_of_or_within negative regulation of cell size 15185396,16286931 Process
56717 GO:0045859 IGI acts_upstream_of_or_within regulation of protein kinase activity 15185396 Process
56717 GO:0048266 IGI involved_in behavioral response to pain 31874168 Process
56717 GO:0048709 IMP acts_upstream_of oligodendrocyte differentiation 25411504 Process
56717 GO:0048714 IMP acts_upstream_of_or_within positive regulation of oligodendrocyte differentiation 25411504 Process
56717 GO:0048738 IMP acts_upstream_of_or_within cardiac muscle tissue development 25139234 Process
56717 GO:0050731 IMP acts_upstream_of_or_within positive regulation of peptidyl-tyrosine phosphorylation 15467718 Process
56717 GO:0050882 IMP acts_upstream_of_or_within voluntary musculoskeletal movement 25139234 Process
56717 GO:0051496 IDA acts_upstream_of_or_within positive regulation of stress fiber assembly 15467718 Process
56717 GO:0051896 IMP acts_upstream_of_or_within regulation of protein kinase B signaling 25139234 Process
56717 GO:0055006 IMP involved_in cardiac cell development 23342106 Process
56717 GO:0055013 IMP acts_upstream_of_or_within cardiac muscle cell development 25139234 Process
56717 GO:0060048 IMP acts_upstream_of_or_within cardiac muscle contraction 25139234 Process
56717 GO:0070885 IMP acts_upstream_of_or_within negative regulation of calcineurin-NFAT signaling cascade 18347059 Process
56717 GO:0071456 IDA involved_in cellular response to hypoxia 16915281 Process
56717 GO:0090559 IMP acts_upstream_of_or_within regulation of membrane permeability 25139234 Process
56717 GO:1904059 IMP involved_in regulation of locomotor rhythm 29750810 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
56717 GO:0004674 IDA enables protein serine/threonine kinase activity 11707573,18347059,21258367,24011591 Function
56717 GO:0005515 IPI enables protein binding 12150926,16541103,16915281,18046414,18566586,18664580,20801936..... Function
56717 GO:0043022 IDA enables ribosome binding 21045808 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
56717 GO:0005634 IDA located_in nucleus 18347059,18381428 Component
56717 GO:0005829 IDA located_in cytosol 16915281,18347059 Component
56717 GO:0016605 IDA colocalizes_with PML body 16915281 Component
56717 GO:0030425 IDA located_in dendrite 23836929 Component
56717 GO:0031931 IDA part_of TORC1 complex 12718876 Component