Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:56852
• Symbol:RAD18
• Description:RAD18 E3 ubiquitin protein ligase

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
56852	GO:0000403	IDA	enables	Y-form DNA binding	18363965	Function
56852	GO:0005515	IPI	enables	protein binding	18316726,18719106,19549727,21422291,21659603,22036607,22681887.....	Function
56852	GO:0031593	IDA	enables	polyubiquitin modification-dependent protein binding	22742833	Function
56852	GO:0031625	IPI	enables	ubiquitin protein ligase binding	10908344,18363965	Function
56852	GO:0042802	IDA	enables	identical protein binding	25023518	Function
56852	GO:0044877	IPI	enables	protein-containing complex binding	25931565	Function
56852	GO:0140678	EXP	enables	molecular function inhibitor activity	21422291	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
56852	GO:0005634	IDA	located_in	nucleus	15632077,22036607,25023518	Component
56852	GO:0005654	IDA	located_in	nucleoplasm		Component
56852	GO:0005657	IDA	located_in	replication fork	18363965	Component
56852	GO:0005813	IDA	located_in	centrosome	15632077	Component
56852	GO:0016604	IDA	located_in	nuclear body		Component
56852	GO:0035861	IDA	located_in	site of double-strand break	25931565	Component
56852	GO:0042405	IDA	located_in	nuclear inclusion body	22036607	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
56852	GO:0006974	IDA	acts_upstream_of_or_within	DNA damage response	25023518	Process
56852	GO:0006974	IDA	involved_in	DNA damage response	22036607,25931565	Process
56852	GO:0051865	IDA	acts_upstream_of_or_within	protein autoubiquitination	25023518	Process
56852	GO:0051984	IMP	involved_in	positive regulation of chromosome segregation	25931565	Process