Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:57531
• Symbol:HACE1
• Description:HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
57531	GO:0000139	IDA	located_in	Golgi membrane	21988917	Component
57531	GO:0005783	IDA	located_in	endoplasmic reticulum		Component
57531	GO:0016604	IDA	located_in	nuclear body		Component

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
57531	GO:0004842	IDA	enables	ubiquitin-protein transferase activity	21988917,22036506	Function
57531	GO:0005515	IPI	enables	protein binding	22614015,25026213,32296183	Function
57531	GO:0031267	IDA	enables	small GTPase binding	21988917	Function
57531	GO:0031267	IPI	enables	small GTPase binding	22036506	Function

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
57531	GO:0006511	IDA	involved_in	ubiquitin-dependent protein catabolic process	22036506	Process
57531	GO:0007030	IDA	involved_in	Golgi organization	21988917	Process
57531	GO:0016567	IDA	involved_in	protein ubiquitination	21988917	Process
57531	GO:0030334	IMP	involved_in	regulation of cell migration	22036506	Process
57531	GO:0061025	IMP	involved_in	membrane fusion	21988917	Process
57531	GO:0070936	IDA	involved_in	protein K48-linked ubiquitination	22036506	Process