Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:5797
  • Symbol:PTPRM
  • Description:protein tyrosine phosphatase receptor type M

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5797 GO:0001937 IMP involved_in negative regulation of endothelial cell proliferation 18566238 Process
5797 GO:0006470 IDA involved_in protein dephosphorylation 8393854,10809770 Process
5797 GO:0007156 IDA involved_in homophilic cell adhesion via plasma membrane adhesion molecules 8393854 Process
5797 GO:0007165 IDA involved_in signal transduction 15080886 Process
5797 GO:0009410 IDA involved_in response to xenobiotic stimulus 18566238 Process
5797 GO:0010596 IMP involved_in negative regulation of endothelial cell migration 18566238 Process
5797 GO:0010842 IMP involved_in retina layer formation 14623235 Process
5797 GO:0016525 IMP involved_in negative regulation of angiogenesis 18566238 Process
5797 GO:0031175 IDA involved_in neuron projection development 16380380 Process
5797 GO:0031175 IMP involved_in neuron projection development 17276081 Process
5797 GO:0031290 IDA involved_in retinal ganglion cell axon guidance 15080886 Process
5797 GO:0051220 IDA acts_upstream_of_negative_effect cytoplasmic sequestering of protein 10753936 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5797 GO:0004725 IDA enables protein tyrosine phosphatase activity 8393854,17965016,18566238 Function
5797 GO:0005001 IDA enables transmembrane receptor protein tyrosine phosphatase activity 10809770 Function
5797 GO:0005515 IPI enables protein binding 9531566,11278757,16380380 Function
5797 GO:0016791 IDA enables phosphatase activity 10753936 Function
5797 GO:0042802 IPI enables identical protein binding 10809770 Function
5797 GO:0045296 IDA enables cadherin binding 9531566 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5797 GO:0005737 IDA located_in cytoplasm 16380380 Component
5797 GO:0005886 IDA located_in plasma membrane Component
5797 GO:0005911 IDA is_active_in cell-cell junction 10753936 Component
5797 GO:0005911 IDA located_in cell-cell junction 15491993,16380380 Component
5797 GO:0005912 IDA located_in adherens junction 17965016 Component
5797 GO:0030027 IDA located_in lamellipodium 15706045 Component
5797 GO:0043232 IDA is_active_in intracellular non-membrane-bounded organelle 17761881 Component
5797 GO:0048471 IDA located_in perinuclear region of cytoplasm 15491993 Component