Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5888
• Symbol:RAD51
• Description:RAD51 recombinase

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
5888	GO:0000150	IDA	enables	DNA strand exchange activity	18417535	Function
5888	GO:0003682	IDA	enables	chromatin binding	23401855	Function
5888	GO:0003690	IDA	enables	double-stranded DNA binding	7988572	Function
5888	GO:0003690	IMP	enables	double-stranded DNA binding	26681308	Function
5888	GO:0003697	IDA	enables	single-stranded DNA binding	7988572	Function
5888	GO:0003697	IMP	enables	single-stranded DNA binding	26681308	Function
5888	GO:0005515	IPI	enables	protein binding	8675009,9380510,9396801,9461559,9560268,9660962,10551859,11309.....	Function
5888	GO:0005524	IDA	enables	ATP binding	16428451	Function
5888	GO:0017116	IDA	enables	single-stranded DNA helicase activity	7988572,8929543	Function
5888	GO:0017116	IMP	enables	single-stranded DNA helicase activity	26681308	Function
5888	GO:0019899	IPI	enables	enzyme binding	23401855	Function
5888	GO:0042802	IPI	enables	identical protein binding	9396801,9469824,9660962,12442171,19622740,19628690,25282148,27.....	Function
5888	GO:0070182	IPI	enables	DNA polymerase binding	19995904	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
5888	GO:0000152	IDA	part_of	nuclear ubiquitin ligase complex	14636569	Component
5888	GO:0000228	IDA	located_in	nuclear chromosome	23754376	Component
5888	GO:0000781	IDA	located_in	chromosome, telomeric region	21076401	Component
5888	GO:0000785	IDA	part_of	chromatin	25585578,26323318	Component
5888	GO:0000800	IDA	located_in	lateral element	9774970	Component
5888	GO:0005634	IDA	located_in	nucleus	12442171,14636569,16215984,18417535,25585578,26323318,26681308.....	Component
5888	GO:0005737	IDA	located_in	cytoplasm	16215984,25585578,26681308	Component
5888	GO:0005739	IDA	located_in	mitochondrion	20413593	Component
5888	GO:0016605	IDA	located_in	PML body	11309417	Component
5888	GO:0032991	IDA	part_of	protein-containing complex	16990250,26833090	Component
5888	GO:0035861	IDA	is_active_in	site of double-strand break	27797818	Component
5888	GO:0035861	IDA	located_in	site of double-strand break	24550317	Component
5888	GO:0048471	IDA	located_in	perinuclear region of cytoplasm	16215984	Component
5888	GO:0099182	IDA	is_active_in	presynaptic intermediate filament cytoskeleton	18003859	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
5888	GO:0000724	IDA	acts_upstream_of_or_within	double-strand break repair via homologous recombination	16428451	Process
5888	GO:0000724	IDA	involved_in	double-strand break repair via homologous recombination	17996710,17996711,18417535,27239033	Process
5888	GO:0000724	IMP	involved_in	double-strand break repair via homologous recombination	22778135,23509288,26681308	Process
5888	GO:0000730	IMP	involved_in	DNA recombinase assembly	26681308	Process
5888	GO:0006268	IDA	involved_in	DNA unwinding involved in DNA replication	7988572	Process
5888	GO:0006974	IDA	involved_in	DNA damage response	17996710,17996711,23509288,25585578,27239033	Process
5888	GO:0006974	IMP	involved_in	DNA damage response	26681308	Process
5888	GO:0010569	IDA	involved_in	regulation of double-strand break repair via homologous recombination	23754376	Process
5888	GO:0031297	IDA	involved_in	replication fork processing	18417535,25585578	Process
5888	GO:0031297	IMP	involved_in	replication fork processing	22778135	Process
5888	GO:0036297	IMP	involved_in	interstrand cross-link repair	26253028	Process
5888	GO:0051106	IDA	involved_in	positive regulation of DNA ligation	8929543	Process
5888	GO:0071479	IDA	involved_in	cellular response to ionizing radiation	23509288,23754376	Process
5888	GO:0071479	IMP	involved_in	cellular response to ionizing radiation	14636569	Process
5888	GO:0072757	IDA	involved_in	cellular response to camptothecin	23509288	Process