Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:5894
  • Symbol:RAF1
  • Description:Raf-1 proto-oncogene, serine/threonine kinase

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5894 GO:0004674 IDA enables protein serine/threonine kinase activity 19667065 Function
5894 GO:0005515 IPI enables protein binding 7644510,7760835,7791872,7882972,7935795,7939632,8085158,833218..... Function
5894 GO:0019899 IPI enables enzyme binding 23509299 Function
5894 GO:0031267 IPI NOT enables small GTPase binding 12194967 Function
5894 GO:0042802 IPI enables identical protein binding 17979178,20130576,22169110,22510884 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5894 GO:0005737 IDA located_in cytoplasm 17724343 Component
5894 GO:0005794 IPI located_in Golgi apparatus 17724343 Component
5894 GO:0005829 IDA located_in cytosol 16009725 Component
5894 GO:0005886 IDA colocalizes_with plasma membrane 16009725 Component
5894 GO:0005886 IDA located_in plasma membrane 17724343 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
5894 GO:0007190 IDA involved_in activation of adenylate cyclase activity 15385642 Process
5894 GO:0008285 IDA involved_in negative regulation of cell population proliferation 9765203 Process
5894 GO:0031333 IDA involved_in negative regulation of protein-containing complex assembly 19667065 Process
5894 GO:0033138 IDA involved_in positive regulation of peptidyl-serine phosphorylation 19667065 Process
5894 GO:0043066 IDA involved_in negative regulation of apoptotic process 19667065 Process
5894 GO:0043410 IDA involved_in positive regulation of MAPK cascade 10644344 Process