Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:59338
• Symbol:PLEKHA1
• Description:pleckstrin homology domain containing A1

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
59338	GO:0005515	IPI	enables	protein binding	11802782,18654987	Function
59338	GO:0030165	IPI	enables	PDZ domain binding	11802782,14516276,15485858	Function
59338	GO:0043325	IDA	enables	phosphatidylinositol-3,4-bisphosphate binding	11001876,17823121	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
59338	GO:0005654	IDA	located_in	nucleoplasm		Component
59338	GO:0005737	IDA	located_in	cytoplasm	12101241,14516276	Component
59338	GO:0005829	IDA	located_in	cytosol		Component
59338	GO:0005886	IDA	located_in	plasma membrane	12101241,14516276	Component
59338	GO:0032587	IDA	located_in	ruffle membrane	12101241	Component
59338	GO:0070062	HDA	located_in	extracellular exosome	19056867	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
59338	GO:0014065	IDA	involved_in	phosphatidylinositol 3-kinase signaling	12101241	Process
59338	GO:0031529	IDA	involved_in	ruffle organization	15485858	Process
59338	GO:0045184	IDA	involved_in	establishment of protein localization	14516276	Process
59338	GO:0050853	IDA	involved_in	B cell receptor signaling pathway	12101241	Process
59338	GO:0051898	IMP	involved_in	negative regulation of protein kinase B signaling	14516276	Process
59338	GO:0070301	IDA	involved_in	cellular response to hydrogen peroxide	14516276	Process