Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:60
• Symbol:ACTB
• Description:actin beta

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
60	GO:0000785	HDA	part_of	chromatin	16217013	Component
60	GO:0000786	IDA	part_of	nucleosome	27153538	Component
60	GO:0005615	HDA	located_in	extracellular space	16502470,22664934,23580065	Component
60	GO:0005634	IDA	located_in	nucleus	11687588	Component
60	GO:0005737	IDA	located_in	cytoplasm	24327345	Component
60	GO:0005856	IDA	located_in	cytoskeleton	24327345	Component
60	GO:0005911	IMP	located_in	cell-cell junction	25753039	Component
60	GO:0005912	IDA	located_in	adherens junction	22855531	Component
60	GO:0005925	HDA	located_in	focal adhesion	21423176	Component
60	GO:0015629	IDA	located_in	actin cytoskeleton	11687588	Component
60	GO:0016020	HDA	located_in	membrane	19946888	Component
60	GO:0030027	IDA	located_in	lamellipodium	24415753	Component
60	GO:0031982	HDA	located_in	vesicle	19190083	Component
60	GO:0032991	HDA	part_of	protein-containing complex	16217013	Component
60	GO:0032991	IDA	part_of	protein-containing complex	11687588,24415753	Component
60	GO:0035267	IDA	part_of	NuA4 histone acetyltransferase complex	10966108,27153538	Component
60	GO:0036464	IDA	located_in	cytoplasmic ribonucleoprotein granule	15121898	Component
60	GO:0043296	IDA	located_in	apical junction complex	22855531	Component
60	GO:0070062	HDA	located_in	extracellular exosome	11487543,19199708,20458337,21362503,23533145	Component
60	GO:0070160	IDA	located_in	tight junction	22855531	Component
60	GO:0072562	HDA	located_in	blood microparticle	22516433	Component
60	GO:0098871	IDA	is_active_in	postsynaptic actin cytoskeleton	18341992	Component
60	GO:0098871	IMP	is_active_in	postsynaptic actin cytoskeleton	18341992	Component
60	GO:0098978	EXP	is_active_in	glutamatergic synapse	18341992	Component
60	GO:0098978	IDA	is_active_in	glutamatergic synapse	18341992	Component
60	GO:0098978	IMP	is_active_in	glutamatergic synapse	18341992	Component
60	GO:1990904	IDA	part_of	ribonucleoprotein complex	17289661	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
60	GO:0001738	IMP	involved_in	morphogenesis of a polarized epithelium	22855531	Process
60	GO:0001895	HEP	involved_in	retina homeostasis	23580065	Process
60	GO:0006338	HDA	involved_in	chromatin remodeling	16217013	Process
60	GO:0007163	IMP	involved_in	establishment or maintenance of cell polarity	22855531	Process
60	GO:0021762	HEP	involved_in	substantia nigra development	22926577	Process
60	GO:0022898	IGI	involved_in	regulation of transmembrane transporter activity	18331289	Process
60	GO:0034333	IMP	involved_in	adherens junction assembly	22855531	Process
60	GO:0043967	IDA	involved_in	histone H4 acetylation	27153538	Process
60	GO:0043968	IDA	involved_in	histone H2A acetylation	27153538	Process
60	GO:0045176	IMP	involved_in	apical protein localization	22855531	Process
60	GO:0048870	IMP	involved_in	cell motility	6202424	Process
60	GO:0051621	IGI	involved_in	regulation of norepinephrine uptake	18331289	Process
60	GO:0051726	IMP	involved_in	regulation of cell cycle	27153538	Process
60	GO:0070527	HMP	involved_in	platelet aggregation	23382103	Process
60	GO:0071896	IMP	involved_in	protein localization to adherens junction	22855531	Process
60	GO:0072749	IMP	involved_in	cellular response to cytochalasin B	6202424	Process
60	GO:0098974	IDA	involved_in	postsynaptic actin cytoskeleton organization	18341992	Process
60	GO:0150111	IMP	involved_in	regulation of transepithelial transport	22855531	Process
60	GO:1903076	IMP	involved_in	regulation of protein localization to plasma membrane	18331289	Process
60	GO:1905168	IDA	involved_in	positive regulation of double-strand break repair via homologous recombination	27153538	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
60	GO:0005515	IPI	enables	protein binding	11687588,14592989,15047060,15161933,15328537,16049941,16189514.....	Function
60	GO:0019894	IPI	enables	kinesin binding	18680169	Function
60	GO:0019901	IPI	enables	protein kinase binding	24327345	Function
60	GO:0030957	IPI	enables	Tat protein binding	16687403	Function
60	GO:0031492	HDA	contributes_to	nucleosomal DNA binding	16217013	Function
60	GO:0042802	IPI	enables	identical protein binding	16189514,17404223,18234857,19000816,20383143,21516116,25416956.....	Function
60	GO:0050998	IPI	enables	nitric-oxide synthase binding	17502619	Function
60	GO:0098973	EXP	enables	structural constituent of postsynaptic actin cytoskeleton	18341992	Function
60	GO:0098973	IDA	enables	structural constituent of postsynaptic actin cytoskeleton	18341992	Function
60	GO:0098973	IMP	enables	structural constituent of postsynaptic actin cytoskeleton	18341992	Function