GeneID | GO_ID | Evidence | Qualifier | GO_term | Pubmed ID | Category | 6331 | GO:0001518 | IDA | part_of | voltage-gated sodium channel complex | 19808477,20042427,21051419 | Component | 6331 | GO:0005654 | IDA | located_in | nucleoplasm | Component | 6331 | GO:0005730 | IDA | located_in | nucleolus | Component | 6331 | GO:0005783 | IDA | located_in | endoplasmic reticulum | 22529811 | Component | 6331 | GO:0005886 | IDA | located_in | plasma membrane | 16728661,17060380,22529811 | Component | 6331 | GO:0005886 | IMP | located_in | plasma membrane | 23085483,26279430 | Component | 6331 | GO:0005901 | IDA | located_in | caveola | 23420830 | Component | 6331 | GO:0009986 | IDA | located_in | cell surface | 14500339,19666841,19943616 | Component | 6331 | GO:0014704 | IDA | located_in | intercalated disc | 15579534 | Component | 6331 | GO:0016020 | IDA | located_in | membrane | 19074138 | Component | 6331 | GO:0030018 | IDA | located_in | Z disc | 19943616 | Component | 6331 | GO:0030315 | IDA | located_in | T-tubule | 15579534 | Component | 6331 | GO:0042383 | IDA | located_in | sarcolemma | 17060380 | Component |
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GeneID | GO_ID | Evidence | Qualifier | GO_term | Pubmed ID | Category | 6331 | GO:0002027 | IMP | involved_in | regulation of heart rate | 10471492,18065446,18616619,21895525,22529811,23085483,26279430..... | Process | 6331 | GO:0006814 | IDA | involved_in | sodium ion transport | 19074138,22514276 | Process | 6331 | GO:0010765 | IDA | involved_in | positive regulation of sodium ion transport | 14500339,18065446,19808477,22529811 | Process | 6331 | GO:0035725 | IDA | involved_in | sodium ion transmembrane transport | 14500339,19943616,21051419 | Process | 6331 | GO:0035725 | IMP | involved_in | sodium ion transmembrane transport | 21895525,23085483,26279430,26392562 | Process | 6331 | GO:0051899 | IDA | involved_in | membrane depolarization | 14500339,21051419,21895525 | Process | 6331 | GO:0060048 | IMP | involved_in | cardiac muscle contraction | 18065446,21895525,22529811 | Process | 6331 | GO:0060307 | IMP | involved_in | regulation of ventricular cardiac muscle cell membrane repolarization | 7889574 | Process | 6331 | GO:0060371 | IMP | involved_in | regulation of atrial cardiac muscle cell membrane depolarization | 19167345,22247482 | Process | 6331 | GO:0060372 | IMP | involved_in | regulation of atrial cardiac muscle cell membrane repolarization | 19167345 | Process | 6331 | GO:0060373 | IMP | involved_in | regulation of ventricular cardiac muscle cell membrane depolarization | 7889574,18065446,22529811 | Process | 6331 | GO:0071277 | IDA | involved_in | cellular response to calcium ion | 19074138 | Process | 6331 | GO:0086002 | IMP | involved_in | cardiac muscle cell action potential involved in contraction | 21895525 | Process | 6331 | GO:0086004 | IMP | involved_in | regulation of cardiac muscle cell contraction | 22529811 | Process | 6331 | GO:0086005 | IMP | involved_in | ventricular cardiac muscle cell action potential | 22529811 | Process | 6331 | GO:0086010 | IDA | involved_in | membrane depolarization during action potential | 14500339,18065446,22529811 | Process | 6331 | GO:0086012 | IMP | involved_in | membrane depolarization during cardiac muscle cell action potential | 21895525 | Process | 6331 | GO:0086014 | IMP | involved_in | atrial cardiac muscle cell action potential | 18065446 | Process | 6331 | GO:0086015 | IMP | involved_in | SA node cell action potential | 18616619 | Process | 6331 | GO:0086016 | IMP | involved_in | AV node cell action potential | 18616619 | Process | 6331 | GO:0086043 | IMP | involved_in | bundle of His cell action potential | 18065446 | Process | 6331 | GO:0086045 | IMP | involved_in | membrane depolarization during AV node cell action potential | 18616619 | Process | 6331 | GO:0086046 | IMP | involved_in | membrane depolarization during SA node cell action potential | 18616619 | Process | 6331 | GO:0086047 | IMP | involved_in | membrane depolarization during Purkinje myocyte cell action potential | 22766342 | Process | 6331 | GO:0086048 | IMP | involved_in | membrane depolarization during bundle of His cell action potential | 18065446 | Process | 6331 | GO:0086067 | IMP | involved_in | AV node cell to bundle of His cell communication | 10471492 | Process | 6331 | GO:0086091 | IMP | involved_in | regulation of heart rate by cardiac conduction | 21895525 | Process | 6331 | GO:0098912 | IMP | involved_in | membrane depolarization during atrial cardiac muscle cell action potential | 18065446 | Process | 6331 | GO:1902305 | IDA | involved_in | regulation of sodium ion transmembrane transport | 18591664 | Process |
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GeneID | GO_ID | Evidence | Qualifier | GO_term | Pubmed ID | Category | 6331 | GO:0005248 | IDA | enables | voltage-gated sodium channel activity | 14500339,19074138,19808477,19943616,21895525,22514276..... | Function | 6331 | GO:0005248 | IMP | enables | voltage-gated sodium channel activity | 23085483,26279430,26392562 | Function | 6331 | GO:0005515 | IPI | enables | protein binding | 16728661,16930557,18184654,18591664,19943616,22514276,22705208..... | Function | 6331 | GO:0005516 | IPI | enables | calmodulin binding | 21167176 | Function | 6331 | GO:0017134 | IPI | enables | fibroblast growth factor binding | 12401812 | Function | 6331 | GO:0019899 | IPI | enables | enzyme binding | 19666841 | Function | 6331 | GO:0019901 | IPI | enables | protein kinase binding | 22514276 | Function | 6331 | GO:0019904 | IPI | enables | protein domain specific binding | 19943616 | Function | 6331 | GO:0030506 | IDA | enables | ankyrin binding | 15579534 | Function | 6331 | GO:0031625 | IPI | enables | ubiquitin protein ligase binding | 15217910 | Function | 6331 | GO:0044325 | IPI | enables | transmembrane transporter binding | 17592081,20042427,24998131 | Function | 6331 | GO:0050998 | IPI | enables | nitric-oxide synthase binding | 18591664 | Function | 6331 | GO:0086006 | IDA | enables | voltage-gated sodium channel activity involved in cardiac muscle cell action potential | 18065446 | Function | 6331 | GO:0086006 | IMP | enables | voltage-gated sodium channel activity involved in cardiac muscle cell action potential | 18616619,21895525,22529811 | Function | 6331 | GO:0086060 | IMP | enables | voltage-gated sodium channel activity involved in AV node cell action potential | 18616619 | Function | 6331 | GO:0086061 | IMP | enables | voltage-gated sodium channel activity involved in bundle of His cell action potential | 18065446 | Function | 6331 | GO:0086062 | IMP | enables | voltage-gated sodium channel activity involved in Purkinje myocyte action potential | 22766342 | Function | 6331 | GO:0086063 | IMP | enables | voltage-gated sodium channel activity involved in SA node cell action potential | 18616619 | Function | 6331 | GO:0097110 | IPI | enables | scaffold protein binding | 17060380 | Function |
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