Gene Ontology

Gene Info

• Species:Rat (Rattus norvegicus)
• GeneID:64044
• Symbol:Casp8
• Description:caspase 8

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
64044	GO:0004197	IDA	enables	cysteine-type endopeptidase activity	16493077	Function
64044	GO:0005123	IPI	enables	death receptor binding	17518537	Function
64044	GO:0005164	IPI	enables	tumor necrosis factor receptor binding	20649583	Function
64044	GO:0005515	IPI	enables	protein binding	12191471,19001025	Function
64044	GO:0044877	IPI	enables	protein-containing complex binding	17518537	Function

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
64044	GO:0016485	IDA	involved_in	protein processing	16493077	Process
64044	GO:0032025	IEP	involved_in	response to cobalt ion	18598848	Process
64044	GO:0032355	IEP	involved_in	response to estradiol	18598848	Process
64044	GO:0032496	IEP	involved_in	response to lipopolysaccharide	18289516	Process
64044	GO:0043525	IMP	involved_in	positive regulation of neuron apoptotic process	10197541	Process
64044	GO:0045471	IDA	involved_in	response to ethanol	18269875	Process
64044	GO:0071407	IEP	involved_in	cellular response to organic cyclic compound	16987298	Process

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
64044	GO:0031264	IDA	part_of	death-inducing signaling complex	17518537	Component
64044	GO:0031265	IDA	part_of	CD95 death-inducing signaling complex	16493077	Component
64044	GO:0032991	IDA	part_of	protein-containing complex	15590916	Component
64044	GO:0044297	IDA	located_in	cell body	18096138	Component