Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:6419
  • Symbol:SETMAR
  • Description:SET domain and mariner transposase fusion gene

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6419 GO:0000014 IMP enables single-stranded DNA endodeoxyribonuclease activity 24573677 Function
6419 GO:0003677 IDA enables DNA binding 20521842 Function
6419 GO:0003690 IMP enables double-stranded DNA binding 24573677 Function
6419 GO:0003697 IMP enables single-stranded DNA binding 24573677 Function
6419 GO:0004519 IDA enables endonuclease activity 20620605,21491884 Function
6419 GO:0004519 IMP enables endonuclease activity 22231448 Function
6419 GO:0005515 IPI enables protein binding 19390626,20457750,20521842,20620605 Function
6419 GO:0042800 IDA enables histone H3K4 methyltransferase activity 16332963 Function
6419 GO:0042803 IPI enables protein homodimerization activity 20521842 Function
6419 GO:0044547 IPI enables DNA topoisomerase binding 18790802,20457750 Function
6419 GO:0046975 IDA enables histone H3K36 methyltransferase activity 16332963 Function
6419 GO:0046975 IMP enables histone H3K36 methyltransferase activity 21187428,22231448 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6419 GO:0000729 IDA involved_in DNA double-strand break processing 21491884 Process
6419 GO:0006303 IDA involved_in double-strand break repair via nonhomologous end joining 16332963 Process
6419 GO:0006303 IMP involved_in double-strand break repair via nonhomologous end joining 18263876,21187428,24573677 Process
6419 GO:0006308 IDA involved_in DNA catabolic process 20521842,21491884 Process
6419 GO:0006308 IMP involved_in DNA catabolic process 24573677 Process
6419 GO:0008283 IMP involved_in cell population proliferation 20457750 Process
6419 GO:0015074 IMP involved_in DNA integration 16332963,24573677 Process
6419 GO:0031297 IMP involved_in replication fork processing 20457750,22231448,24573677 Process
6419 GO:0044774 IMP involved_in mitotic DNA integrity checkpoint signaling 18790802 Process
6419 GO:0090305 IMP involved_in nucleic acid phosphodiester bond hydrolysis 22231448 Process
6419 GO:2000373 IDA involved_in positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity 18790802 Process
6419 GO:2000373 IMP involved_in positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity 20457750 Process
6419 GO:2001034 IDA involved_in positive regulation of double-strand break repair via nonhomologous end joining 20620605,21491884 Process
6419 GO:2001251 IDA involved_in negative regulation of chromosome organization 20620605 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6419 GO:0000793 IDA colocalizes_with condensed chromosome 18790802 Component
6419 GO:0005634 IDA located_in nucleus 22231448 Component
6419 GO:0005730 IDA located_in nucleolus Component
6419 GO:0035861 IDA located_in site of double-strand break 18263876,21187428 Component
6419 GO:0035861 IMP located_in site of double-strand break 22231448 Component