Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:6424
  • Symbol:SFRP4
  • Description:secreted frizzled related protein 4

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6424 GO:0002092 IDA involved_in positive regulation of receptor internalization 16151791 Process
6424 GO:0008285 IMP involved_in negative regulation of cell population proliferation 14760084,15705870 Process
6424 GO:0010628 IDA involved_in positive regulation of gene expression 18938133 Process
6424 GO:0043065 IMP involved_in positive regulation of apoptotic process 15705870 Process
6424 GO:0043433 IDA involved_in negative regulation of DNA-binding transcription factor activity 18945944 Process
6424 GO:0045606 IDA involved_in positive regulation of epidermal cell differentiation 18938133 Process
6424 GO:0055062 IDA involved_in phosphate ion homeostasis 12952927,16151791 Process
6424 GO:0060349 IMP involved_in bone morphogenesis 27355534 Process
6424 GO:0090090 IDA involved_in negative regulation of canonical Wnt signaling pathway 18945944 Process
6424 GO:0090090 IMP involved_in negative regulation of canonical Wnt signaling pathway 14760084,15705870 Process
6424 GO:0090263 IGI acts_upstream_of_or_within positive regulation of canonical Wnt signaling pathway 18166153 Process
6424 GO:1902174 IDA involved_in positive regulation of keratinocyte apoptotic process 18938133 Process
6424 GO:2000119 IDA involved_in negative regulation of sodium-dependent phosphate transport 12952927,16151791 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6424 GO:0005515 IPI enables protein binding 15607035,32296183,32814053 Function
6424 GO:0017147 IDA enables Wnt-protein binding 17462603 Function
6424 GO:0017147 IPI enables Wnt-protein binding 17462603 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6424 GO:0005615 IDA located_in extracellular space 14760084 Component
6424 GO:0005634 IDA located_in nucleus 18938133 Component
6424 GO:0005737 IDA located_in cytoplasm 11793365,14760084,18938133 Component
6424 GO:0009986 IDA located_in cell surface 14760084 Component