Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:6469
  • Symbol:SHH
  • Description:sonic hedgehog signaling molecule

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6469 GO:0002320 IMP involved_in lymphoid progenitor cell differentiation 14764698 Process
6469 GO:0007224 IDA involved_in smoothened signaling pathway 31279575 Process
6469 GO:0007224 IEP involved_in smoothened signaling pathway 17850284 Process
6469 GO:0008284 IDA involved_in positive regulation of cell population proliferation 11331587 Process
6469 GO:0043369 IDA involved_in CD4-positive or CD8-positive, alpha-beta T cell lineage commitment 17227833 Process
6469 GO:0045880 IDA involved_in positive regulation of smoothened signaling pathway 19561609,24342078 Process
6469 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 10654605 Process
6469 GO:0048745 IEP involved_in smooth muscle tissue development 17850284 Process
6469 GO:0051781 IDA involved_in positive regulation of cell division 11331587 Process
6469 GO:0060738 IDA acts_upstream_of_or_within epithelial-mesenchymal signaling involved in prostate gland development 12221011 Process
6469 GO:0061189 IDA involved_in positive regulation of sclerotome development 10654605 Process
6469 GO:0072205 IEP involved_in metanephric collecting duct development 17850284 Process
6469 GO:1900180 IDA involved_in regulation of protein localization to nucleus 11331587 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6469 GO:0005113 IDA enables patched binding 8906787,11472839 Function
6469 GO:0005509 IDA enables calcium ion binding 19561609 Function
6469 GO:0005515 IPI enables protein binding 19561609,29954986,29995851,30139912 Function
6469 GO:0008270 IDA enables zinc ion binding 19561609 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6469 GO:0005615 IDA located_in extracellular space 19561609 Component
6469 GO:0005783 IDA located_in endoplasmic reticulum 18534984 Component
6469 GO:0005794 IDA located_in Golgi apparatus 18534984 Component
6469 GO:0062023 HDA located_in collagen-containing extracellular matrix 28344315 Component