Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:64750
• Symbol:SMURF2
• Description:SMAD specific E3 ubiquitin protein ligase 2

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
64750	GO:0000151	IDA	part_of	ubiquitin ligase complex	14755250	Component
64750	GO:0016607	IDA	located_in	nuclear speck		Component

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
64750	GO:0004842	IDA	enables	ubiquitin-protein transferase activity	14755250	Function
64750	GO:0005515	IPI	enables	protein binding	14755250,15231748,17719543,18729074,18985028,20676133,20937913.....	Function
64750	GO:0042802	IPI	enables	identical protein binding	15231748,17719543	Function
64750	GO:0046332	IPI	enables	SMAD binding	19122240	Function

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
64750	GO:0006511	IDA	involved_in	ubiquitin-dependent protein catabolic process	14755250,19122240	Process
64750	GO:0030512	IDA	involved_in	negative regulation of transforming growth factor beta receptor signaling pathway	19255252	Process
64750	GO:1901165	IDA	involved_in	positive regulation of trophoblast cell migration	19255252	Process