Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:6495
• Symbol:SIX1
• Description:SIX homeobox 1

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6495	GO:0000976	IDA	enables	transcription cis-regulatory region binding	16670092	Function
6495	GO:0000978	IDA	enables	RNA polymerase II cis-regulatory region sequence-specific DNA binding	15141091	Function
6495	GO:0000978	IMP	enables	RNA polymerase II cis-regulatory region sequence-specific DNA binding	15141091	Function
6495	GO:0001228	IDA	enables	DNA-binding transcription activator activity, RNA polymerase II-specific	15141091	Function
6495	GO:0001228	IMP	enables	DNA-binding transcription activator activity, RNA polymerase II-specific	15141091	Function
6495	GO:0003677	IDA	enables	DNA binding	19497856	Function
6495	GO:0003700	IDA	enables	DNA-binding transcription factor activity	19497856	Function
6495	GO:0005515	IPI	enables	protein binding	15141091,16189514,19497856,20211142,21516116,23435380,25416956.....	Function
6495	GO:0043565	IDA	enables	sequence-specific DNA binding	15141091	Function
6495	GO:1990837	IDA	enables	sequence-specific double-stranded DNA binding	28473536	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6495	GO:0005634	IDA	located_in	nucleus	16670092,19497856	Component
6495	GO:0005654	IDA	located_in	nucleoplasm		Component
6495	GO:0005730	IDA	located_in	nucleolus		Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6495	GO:0034504	IDA	involved_in	protein localization to nucleus	19497856	Process
6495	GO:0045893	IMP	involved_in	positive regulation of DNA-templated transcription	27923061	Process
6495	GO:0045944	IDA	involved_in	positive regulation of transcription by RNA polymerase II	15141091	Process
6495	GO:0045944	IMP	involved_in	positive regulation of transcription by RNA polymerase II	15141091	Process