Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:6532
• Symbol:SLC6A4
• Description:solute carrier family 6 member 4

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6532	GO:0005178	IDA	enables	integrin binding	18317590	Function
6532	GO:0005335	IDA	enables	serotonin:sodium:chloride symporter activity	8987735,10407194,17506858	Function
6532	GO:0005335	IMP	enables	serotonin:sodium:chloride symporter activity	12869649	Function
6532	GO:0005515	IPI	enables	protein binding	11343649,12177201,16870614,16882008,18317590	Function
6532	GO:0008504	IDA	enables	monoamine transmembrane transporter activity	16024787	Function
6532	GO:0015297	IDA	enables	antiporter activity	27756841	Function
6532	GO:0031402	IDA	enables	sodium ion binding	34851672	Function
6532	GO:0051378	IDA	enables	serotonin binding	34851672	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6532	GO:0005886	IDA	located_in	plasma membrane	12869649,16870614,17506858,18317590	Component
6532	GO:0012505	IDA	located_in	endomembrane system	17506858	Component
6532	GO:0045121	IDA	located_in	membrane raft	16870614	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6532	GO:0009636	IDA	involved_in	response to toxic substance	17575980	Process
6532	GO:0015844	IDA	acts_upstream_of_or_within	monoamine transport	16024787	Process
6532	GO:0051610	IDA	involved_in	serotonin uptake	8987735,16870614,17506858,18317590,21730057,27756841.....	Process
6532	GO:0051610	IMP	involved_in	serotonin uptake	7681602	Process
6532	GO:0090067	IMP	involved_in	regulation of thalamus size	18378990	Process