Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:6608
• Symbol:SMO
• Description:smoothened, frizzled class receptor

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6608	GO:0004862	IDA	enables	cAMP-dependent protein kinase inhibitor activity	36202993	Function
6608	GO:0005113	IPI	enables	patched binding	9811851	Function
6608	GO:0005515	IPI	enables	protein binding	19592253,21659505	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6608	GO:0005794	IDA	colocalizes_with	Golgi apparatus	11278759	Component
6608	GO:0005886	IDA	located_in	plasma membrane	19304771	Component
6608	GO:0005901	IDA	colocalizes_with	caveola	11278759	Component
6608	GO:0005929	IDA	located_in	cilium	27727273,32413283	Component
6608	GO:0043231	IDA	located_in	intracellular membrane-bounded organelle	11278759	Component
6608	GO:0070062	HDA	located_in	extracellular exosome	19056867,23533145	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
6608	GO:0007224	IDA	involved_in	smoothened signaling pathway	36202993	Process
6608	GO:0007224	IEP	involved_in	smoothened signaling pathway	17850284	Process
6608	GO:0007224	IMP	involved_in	smoothened signaling pathway	9422511,19304771,21177415,32413283	Process
6608	GO:0010628	IMP	involved_in	positive regulation of gene expression	21671467	Process
6608	GO:0030335	IMP	involved_in	positive regulation of cell migration	21671467	Process
6608	GO:0048745	IEP	involved_in	smooth muscle tissue development	17850284	Process
6608	GO:0060242	IMP	involved_in	contact inhibition	9422511	Process