Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:66824
  • Symbol:Pycard
  • Description:PYD and CARD domain containing

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
66824 GO:0002218 IMP involved_in activation of innate immune response 19158675 Process
66824 GO:0002230 IMP involved_in positive regulation of defense response to virus by host 19158675 Process
66824 GO:0002277 IMP involved_in myeloid dendritic cell activation involved in immune response 21892172 Process
66824 GO:0002588 IMP involved_in positive regulation of antigen processing and presentation of peptide antigen via MHC class II 21892172 Process
66824 GO:0006919 IMP acts_upstream_of_or_within activation of cysteine-type endopeptidase activity involved in apoptotic process 17008311 Process
66824 GO:0006954 IMP acts_upstream_of_or_within inflammatory response 15190255 Process
66824 GO:0009617 IMP acts_upstream_of_or_within response to bacterium 24581500 Process
66824 GO:0010506 IMP acts_upstream_of_or_within regulation of autophagy 24581500 Process
66824 GO:0010934 IGI acts_upstream_of macrophage cytokine production 22002608 Process
66824 GO:0030838 IMP involved_in positive regulation of actin filament polymerization 21892172 Process
66824 GO:0031647 IMP involved_in regulation of protein stability 21892172 Process
66824 GO:0032611 IGI acts_upstream_of interleukin-1 beta production 22002608 Process
66824 GO:0032611 IGI acts_upstream_of_or_within interleukin-1 beta production 19158679 Process
66824 GO:0032722 IMP involved_in positive regulation of chemokine production 21487011 Process
66824 GO:0032729 IMP involved_in positive regulation of type II interferon production 21892172 Process
66824 GO:0032731 IDA involved_in positive regulation of interleukin-1 beta production 27270401,29255148 Process
66824 GO:0032731 IGI acts_upstream_of_or_within positive regulation of interleukin-1 beta production 22002608 Process
66824 GO:0032731 IMP acts_upstream_of_or_within positive regulation of interleukin-1 beta production 23997220 Process
66824 GO:0032731 IMP involved_in positive regulation of interleukin-1 beta production 19158675 Process
66824 GO:0032755 IMP involved_in positive regulation of interleukin-6 production 21892172 Process
66824 GO:0042104 IMP involved_in positive regulation of activated T cell proliferation 21892172 Process
66824 GO:0042981 IMP acts_upstream_of_or_within regulation of apoptotic process 15190255 Process
66824 GO:0043087 IMP involved_in regulation of GTPase activity 21892172 Process
66824 GO:0043281 IMP acts_upstream_of_or_within regulation of cysteine-type endopeptidase activity involved in apoptotic process 15190255 Process
66824 GO:0044351 IMP involved_in macropinocytosis 21892172 Process
66824 GO:0050727 IMP acts_upstream_of_or_within regulation of inflammatory response 22002608,22297845 Process
66824 GO:0050729 IDA involved_in positive regulation of inflammatory response 27270401 Process
66824 GO:0050766 IMP involved_in positive regulation of phagocytosis 21892172 Process
66824 GO:0050830 IMP acts_upstream_of_or_within defense response to Gram-positive bacterium 30248149 Process
66824 GO:0060907 IGI acts_upstream_of_or_within positive regulation of macrophage cytokine production 22002608 Process
66824 GO:0070374 IMP involved_in positive regulation of ERK1 and ERK2 cascade 21487011 Process
66824 GO:0097202 IMP involved_in activation of cysteine-type endopeptidase activity 23302887 Process
66824 GO:2000406 IMP involved_in positive regulation of T cell migration 21892172 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
66824 GO:0005515 IPI enables protein binding 15190255,19158679,22801494,23143333,25605870 Function
66824 GO:0042802 IPI enables identical protein binding 24407287 Function
66824 GO:0046983 IMP enables protein dimerization activity 24407287 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
66824 GO:0005576 IDA located_in extracellular region 15190255 Component
66824 GO:0005634 IDA located_in nucleus 21892172,24407287 Component
66824 GO:0005829 IDA located_in cytosol 11139337 Component
66824 GO:0061702 IDA part_of canonical inflammasome complex 30248149 Component
66824 GO:0140738 IDA part_of NLRP6 inflammasome complex 34678144 Component