Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:6790
  • Symbol:AURKA
  • Description:aurora kinase A

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6790 GO:0004672 IDA enables protein kinase activity 14580337,19801554,21600873 Function
6790 GO:0004674 EXP enables protein serine/threonine kinase activity 13678582,18566290,21807936 Function
6790 GO:0004674 IMP enables protein serine/threonine kinase activity 28218735 Function
6790 GO:0005515 IPI enables protein binding 12244051,14580337,15987997,17604723,17726514,17939994,18361916..... Function
6790 GO:0019901 IPI enables protein kinase binding 18615013 Function
6790 GO:0046982 IPI enables protein heterodimerization activity 20460379 Function
6790 GO:0140677 EXP enables molecular function activator activity 12237287 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6790 GO:0005634 IDA located_in nucleus 20531406 Component
6790 GO:0005654 IDA located_in nucleoplasm Component
6790 GO:0005813 IDA located_in centrosome 17726514,21399614,21600873,23213400,25657325,30538148..... Component
6790 GO:0005829 IDA located_in cytosol Component
6790 GO:0005876 IDA colocalizes_with spindle microtubule 19801554 Component
6790 GO:0015630 IDA located_in microtubule cytoskeleton 19801554 Component
6790 GO:0031616 IDA located_in spindle pole centrosome 19801554 Component
6790 GO:0036064 IDA located_in ciliary basal body 17604723 Component
6790 GO:0048471 IDA located_in perinuclear region of cytoplasm 20531406 Component
6790 GO:0072686 IDA located_in mitotic spindle Component
6790 GO:0097431 IDA located_in mitotic spindle pole 25657325 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6790 GO:0006468 IDA acts_upstream_of_or_within protein phosphorylation 21600873 Process
6790 GO:0006468 IDA involved_in protein phosphorylation 21820309 Process
6790 GO:0007051 IMP involved_in spindle organization 21820309 Process
6790 GO:0009611 IDA acts_upstream_of_or_within response to wounding 19435814 Process
6790 GO:0010629 IMP involved_in negative regulation of gene expression 28218735 Process
6790 GO:0018105 IMP involved_in peptidyl-serine phosphorylation 28218735 Process
6790 GO:0031647 IMP involved_in regulation of protein stability 15987997 Process
6790 GO:0032091 IDA involved_in negative regulation of protein binding 21820309 Process
6790 GO:0061523 IMP involved_in cilium disassembly 17604723 Process
6790 GO:0090141 IMP involved_in positive regulation of mitochondrial fission 21822277 Process
6790 GO:0097421 IDA acts_upstream_of_or_within liver regeneration 19435814 Process