Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:6926
  • Symbol:TBX3
  • Description:T-box transcription factor 3

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6926 GO:0000122 IDA involved_in negative regulation of transcription by RNA polymerase II 11689487 Process
6926 GO:0000122 IMP involved_in negative regulation of transcription by RNA polymerase II 12000749,22130515 Process
6926 GO:0001501 IMP involved_in skeletal system development 9207801 Process
6926 GO:0003272 IMP involved_in endocardial cushion formation 22130515 Process
6926 GO:0008284 IDA involved_in positive regulation of cell population proliferation 12032820 Process
6926 GO:0008595 IMP involved_in anterior/posterior axis specification, embryo 9207801 Process
6926 GO:0009887 IDA acts_upstream_of_or_within animal organ morphogenesis 9207801 Process
6926 GO:0030539 IMP involved_in male genitalia development 12116211 Process
6926 GO:0030540 IMP involved_in female genitalia development 12116211 Process
6926 GO:0030879 IMP involved_in mammary gland development 12116211 Process
6926 GO:0032275 IMP involved_in luteinizing hormone secretion 12116211 Process
6926 GO:0035115 IMP involved_in embryonic forelimb morphogenesis 12116211 Process
6926 GO:0035136 IDA acts_upstream_of_or_within forelimb morphogenesis 9207801 Process
6926 GO:0042733 IMP involved_in embryonic digit morphogenesis 9207801,12116211 Process
6926 GO:0043066 IDA involved_in negative regulation of apoptotic process 12032820 Process
6926 GO:0045662 IDA involved_in negative regulation of myoblast differentiation 12032820 Process
6926 GO:0045787 IDA involved_in positive regulation of cell cycle 12032820 Process
6926 GO:0045892 IDA involved_in negative regulation of DNA-templated transcription 10468588,11689487 Process
6926 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 22130515 Process
6926 GO:0046884 IMP involved_in follicle-stimulating hormone secretion 12116211 Process
6926 GO:0048332 IMP involved_in mesoderm morphogenesis 9207801 Process
6926 GO:0060317 IMP involved_in cardiac epithelial to mesenchymal transition 22130515 Process
6926 GO:0060931 IDA involved_in sinoatrial node cell development 22130515 Process
6926 GO:0090398 IDA involved_in cellular senescence 11748239,22002537 Process
6926 GO:1905072 IMP involved_in cardiac jelly development 22130515 Process
6926 GO:2000137 IMP involved_in negative regulation of cell proliferation involved in heart morphogenesis 22130515 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6926 GO:0000978 IDA enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 11689487,12000749,22130515 Function
6926 GO:0001227 IDA enables DNA-binding transcription repressor activity, RNA polymerase II-specific 11689487,22130515 Function
6926 GO:0001228 IDA enables DNA-binding transcription activator activity, RNA polymerase II-specific 22130515 Function
6926 GO:0005515 IPI enables protein binding 22002537,25416956,32296183 Function
6926 GO:0043565 IDA enables sequence-specific DNA binding 11689487 Function
6926 GO:1990837 IDA enables sequence-specific double-stranded DNA binding 28473536 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
6926 GO:0005634 IDA located_in nucleus 11689487 Component