Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:69847
  • Symbol:Wnk4
  • Description:WNK lysine deficient protein kinase 4

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
69847 GO:0002021 IMP involved_in response to dietary excess 22550170,24761002,28314693 Process
69847 GO:0003096 IDA involved_in renal sodium ion transport 14608358 Process
69847 GO:0006468 IGI involved_in protein phosphorylation 28743496 Process
69847 GO:0006468 IMP involved_in protein phosphorylation 22114204,24655003,24761002,31736353,31786261 Process
69847 GO:0006469 IMP involved_in negative regulation of protein kinase activity 30765526 Process
69847 GO:0006821 IDA acts_upstream_of_or_within chloride transport 14769928 Process
69847 GO:0006954 IMP involved_in inflammatory response 31786261 Process
69847 GO:0007165 IMP involved_in signal transduction 21486947 Process
69847 GO:0008104 IDA acts_upstream_of_or_within protein localization 12515852,12671053 Process
69847 GO:0008217 IMP involved_in regulation of blood pressure 16964266,17360470,17488636,19633012 Process
69847 GO:0009410 IGI involved_in response to xenobiotic stimulus 24039833 Process
69847 GO:0010467 IGI involved_in gene expression 28743496 Process
69847 GO:0010467 IMP involved_in gene expression 22114204,22550170,23576762,24206662,24655003,28314693,28365586..... Process
69847 GO:0030644 IMP involved_in intracellular chloride ion homeostasis 30765526 Process
69847 GO:0032147 IDA involved_in activation of protein kinase activity 28096417 Process
69847 GO:0035725 IMP involved_in sodium ion transmembrane transport 24655003,25113964,28365586,31736353 Process
69847 GO:0035932 IMP involved_in aldosterone secretion 22550170 Process
69847 GO:0042116 IMP involved_in macrophage activation 31786261 Process
69847 GO:0045859 IMP involved_in regulation of protein kinase activity 29921588 Process
69847 GO:0050801 IMP involved_in monoatomic ion homeostasis 23576762 Process
69847 GO:0055074 IMP involved_in calcium ion homeostasis 31496133 Process
69847 GO:0070294 IMP involved_in renal sodium ion absorption 16964266,17488636,19633012 Process
69847 GO:0070371 IMP involved_in ERK1 and ERK2 cascade 22114204 Process
69847 GO:0070528 IDA involved_in protein kinase C signaling 28096417 Process
69847 GO:0071466 IMP involved_in cellular response to xenobiotic stimulus 31496133 Process
69847 GO:0071805 IMP involved_in potassium ion transmembrane transport 28365586 Process
69847 GO:0090188 IMP acts_upstream_of_or_within negative regulation of pancreatic juice secretion 21317537 Process
69847 GO:1903077 IDA involved_in negative regulation of protein localization to plasma membrane 17673510 Process
69847 GO:1903764 IMP involved_in regulation of potassium ion export across plasma membrane 16964266 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
69847 GO:0004674 IMP enables protein serine/threonine kinase activity 21486947 Function
69847 GO:0005515 IPI enables protein binding 17360471,21670282,23576762,24434184,24821705,25250572,25313067..... Function
69847 GO:0008200 IDA enables ion channel inhibitor activity 14608358 Function
69847 GO:0031404 IMP enables chloride ion binding 30765526 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
69847 GO:0005737 IDA located_in cytoplasm 14769928 Component
69847 GO:0005923 IDA located_in bicellular tight junction 11498583 Component
69847 GO:0032991 IDA part_of protein-containing complex 25113964 Component
69847 GO:0044297 IMP is_active_in cell body 31736353 Component