Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:7010
  • Symbol:TEK
  • Description:TEK receptor tyrosine kinase

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7010 GO:0001725 IDA colocalizes_with stress fiber 18425119 Component
7010 GO:0005884 IDA colocalizes_with actin filament 18425119 Component
7010 GO:0005886 IDA located_in plasma membrane 19689429 Component
7010 GO:0005902 IDA located_in microvillus 19424712 Component
7010 GO:0005911 IDA located_in cell-cell junction 18425120 Component
7010 GO:0009925 IDA located_in basal plasma membrane 18425120 Component
7010 GO:0009986 IDA located_in cell surface 19689429 Component
7010 GO:0016323 IDA located_in basolateral plasma membrane 19424712 Component
7010 GO:0016324 IDA located_in apical plasma membrane 19424712 Component
7010 GO:0034451 IDA located_in centriolar satellite Component
7010 GO:0045121 IDA located_in membrane raft 19615361 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7010 GO:0001934 IDA involved_in positive regulation of protein phosphorylation 15284220 Process
7010 GO:0001934 IMP involved_in positive regulation of protein phosphorylation 15985432,18425120 Process
7010 GO:0002040 IMP involved_in sprouting angiogenesis 14665640 Process
7010 GO:0007169 IDA involved_in transmembrane receptor protein tyrosine kinase signaling pathway 15284220 Process
7010 GO:0010595 IDA involved_in positive regulation of endothelial cell migration 15284220 Process
7010 GO:0010595 IMP involved_in positive regulation of endothelial cell migration 12816861,18425120 Process
7010 GO:0014068 IMP involved_in positive regulation of phosphatidylinositol 3-kinase signaling 18425120,19223473 Process
7010 GO:0016525 IMP involved_in negative regulation of angiogenesis 18425120 Process
7010 GO:0018108 IDA involved_in peptidyl-tyrosine phosphorylation 11513602 Process
7010 GO:0032878 IMP involved_in regulation of establishment or maintenance of cell polarity 18425119 Process
7010 GO:0034446 IMP involved_in substrate adhesion-dependent cell spreading 18425119 Process
7010 GO:0035556 IMP involved_in intracellular signal transduction 12816861 Process
7010 GO:0043552 IMP involved_in positive regulation of phosphatidylinositol 3-kinase activity 18425120 Process
7010 GO:0045766 IDA involved_in positive regulation of angiogenesis 15284220 Process
7010 GO:0045766 IMP involved_in positive regulation of angiogenesis 18425120 Process
7010 GO:0046777 IDA involved_in protein autophosphorylation 11513602 Process
7010 GO:0048014 IDA involved_in Tie signaling pathway 15284220,19223473 Process
7010 GO:0051894 IMP involved_in positive regulation of focal adhesion assembly 18425120 Process
7010 GO:0051897 IDA involved_in positive regulation of protein kinase B signaling 19615361 Process
7010 GO:0051897 IMP involved_in positive regulation of protein kinase B signaling 18425120 Process
7010 GO:0070374 IDA involved_in positive regulation of ERK1 and ERK2 cascade 19615361 Process
7010 GO:0070374 IMP involved_in positive regulation of ERK1 and ERK2 cascade 18425120 Process
7010 GO:1902533 IMP involved_in positive regulation of intracellular signal transduction 19223473 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7010 GO:0004713 IDA enables protein tyrosine kinase activity 11513602 Function
7010 GO:0005515 IPI enables protein binding 8980223,15893672,15985432,16732286,19167335,19451274,19922791,..... Function
7010 GO:0042802 IPI enables identical protein binding 19424712 Function