Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:7048
  • Symbol:TGFBR2
  • Description:transforming growth factor beta receptor 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7048 GO:0003180 IMP involved_in aortic valve morphogenesis 20101701 Process
7048 GO:0006468 IDA involved_in protein phosphorylation 9311995,12015308 Process
7048 GO:0006915 IDA involved_in apoptotic process 17471240 Process
7048 GO:0007179 IDA involved_in transforming growth factor beta receptor signaling pathway 1333888,18453574 Process
7048 GO:0007179 IMP involved_in transforming growth factor beta receptor signaling pathway 1333888 Process
7048 GO:0009410 IDA involved_in response to xenobiotic stimulus 17878231 Process
7048 GO:0010718 IDA involved_in positive regulation of epithelial to mesenchymal transition 26459119 Process
7048 GO:0010862 IDA involved_in positive regulation of pathway-restricted SMAD protein phosphorylation 12065756 Process
7048 GO:0018105 IDA involved_in peptidyl-serine phosphorylation 12015308 Process
7048 GO:0018107 IDA involved_in peptidyl-threonine phosphorylation 12015308 Process
7048 GO:0035909 IMP involved_in aorta morphogenesis 20101701 Process
7048 GO:0048844 IMP involved_in artery morphogenesis 20101701 Process
7048 GO:0060021 IMP involved_in roof of mouth development 20101701 Process
7048 GO:0060389 IDA involved_in pathway-restricted SMAD protein phosphorylation 18453574 Process
7048 GO:0070723 IDA involved_in response to cholesterol 17878231 Process
7048 GO:2000379 IMP involved_in positive regulation of reactive oxygen species metabolic process 20160708 Process
7048 GO:2000563 IDA involved_in positive regulation of CD4-positive, alpha-beta T cell proliferation 17164348 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7048 GO:0004675 IDA enables transmembrane receptor protein serine/threonine kinase activity 12015308 Function
7048 GO:0005024 IDA enables transforming growth factor beta receptor activity 7852346,18453574 Function
7048 GO:0005024 IMP enables transforming growth factor beta receptor activity 1333888 Function
7048 GO:0005515 IPI enables protein binding 7852346,8242742,8555189,8622651,9865696,11278302,11279102,1148..... Function
7048 GO:0005539 IDA enables glycosaminoglycan binding 7852346 Function
7048 GO:0034713 IPI enables type I transforming growth factor beta receptor binding 1333888 Function
7048 GO:0046332 IDA enables SMAD binding 11157754,18453574 Function
7048 GO:0050431 IDA enables transforming growth factor beta binding 7852346,18243111,18453574 Function
7048 GO:0050431 IPI contributes_to transforming growth factor beta binding 7852346 Function
7048 GO:0050431 IPI enables transforming growth factor beta binding 1326540,1333888 Function
7048 GO:0060090 EXP enables molecular adaptor activity 18243111 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7048 GO:0005886 IDA located_in plasma membrane 25893292 Component
7048 GO:0005901 IDA located_in caveola 17878231 Component
7048 GO:0009897 IDA located_in external side of plasma membrane 18453574 Component
7048 GO:0016020 IDA located_in membrane 7852346 Component
7048 GO:0043235 IDA part_of receptor complex 7852346,8774881 Component
7048 GO:0045121 IDA located_in membrane raft 25893292 Component
7048 GO:0070021 IPI part_of transforming growth factor beta ligand-receptor complex 18243111,20207738 Component