Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:7137
• Symbol:TNNI3
• Description:troponin I3, cardiac type

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
7137	GO:0003779	IDA	enables	actin binding	10806205	Function
7137	GO:0005515	IPI	enables	protein binding	10806205,12525172,12721663,12809519,16516408,18986304,21569246.....	Function
7137	GO:0019855	IPI	enables	calcium channel inhibitor activity	12809519	Function
7137	GO:0019901	IPI	enables	protein kinase binding	12721663	Function
7137	GO:0019904	IPI	enables	protein domain specific binding	11984006	Function
7137	GO:0030172	IPI	enables	troponin C binding	7957210,11735257,15542288	Function
7137	GO:0031014	IPI	enables	troponin T binding	15542288	Function
7137	GO:0048306	IPI	enables	calcium-dependent protein binding	7957210	Function
7137	GO:0051015	IPI	enables	actin filament binding	25771144	Function
7137	GO:0140678	EXP	enables	molecular function inhibitor activity	12840750	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
7137	GO:0005861	IDA	part_of	troponin complex	7957210,10806205,10850966,12093807	Component
7137	GO:0097512	IMP	located_in	cardiac myofibril	25771144	Component
7137	GO:1990584	IMP	part_of	cardiac Troponin complex	25771144	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
7137	GO:0010882	IMP	involved_in	regulation of cardiac muscle contraction by calcium ion signaling	25771144	Process
7137	GO:0032780	IDA	involved_in	negative regulation of ATP-dependent activity	7957210,11735257	Process
7137	GO:0032780	IMP	involved_in	negative regulation of ATP-dependent activity	10806205	Process
7137	GO:0055010	IMP	involved_in	ventricular cardiac muscle tissue morphogenesis	11815426,16754800	Process
7137	GO:0060047	IMP	involved_in	heart contraction	12531876	Process
7137	GO:0060048	IMP	involved_in	cardiac muscle contraction	11735257	Process