Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:7251
  • Symbol:TSG101
  • Description:tumor susceptibility 101

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7251 GO:0000813 IDA part_of ESCRT I complex 18005716,20654576,21757351,22232651 Component
7251 GO:0000813 IPI part_of ESCRT I complex 18005716,21757351,32424346 Component
7251 GO:0005730 IDA located_in nucleolus Component
7251 GO:0005737 IDA located_in cytoplasm 18077552 Component
7251 GO:0005768 IDA located_in endosome 17940959 Component
7251 GO:0005769 IDA located_in early endosome 11916981,17229889 Component
7251 GO:0005770 IMP located_in late endosome 15126635 Component
7251 GO:0005829 IDA located_in cytosol Component
7251 GO:0005886 IDA located_in plasma membrane 17940959 Component
7251 GO:0070062 HDA located_in extracellular exosome 19056867,23533145 Component
7251 GO:0070062 IDA located_in extracellular exosome 15326289,16501490,23092844 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7251 GO:0005515 IPI enables protein binding 12802020,12900395,14505570,14519844,15033475,15039775,15218037..... Function
7251 GO:0031625 IPI enables ubiquitin protein ligase binding 17229889 Function
7251 GO:0042803 IPI enables protein homodimerization activity 14519844 Function
7251 GO:0043130 IDA enables ubiquitin binding 11595185,11916981,20654576 Function
7251 GO:0044877 IDA enables protein-containing complex binding 16973552 Function
7251 GO:0046790 IDA enables virion binding 11595185 Function
7251 GO:0048306 IPI enables calcium-dependent protein binding 19520058 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7251 GO:0006858 IMP involved_in extracellular transport 22315426 Process
7251 GO:0007175 IMP involved_in negative regulation of epidermal growth factor-activated receptor activity 16973552 Process
7251 GO:0019076 IMP involved_in viral release from host cell 11595185,15218037 Process
7251 GO:0042059 IMP involved_in negative regulation of epidermal growth factor receptor signaling pathway 16554368 Process
7251 GO:0043162 IDA involved_in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 15611048 Process
7251 GO:0043162 IMP involved_in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 21757351 Process
7251 GO:0043405 IMP involved_in regulation of MAP kinase activity 17714434 Process
7251 GO:0046755 IMP involved_in viral budding 15126635,18005716 Process
7251 GO:1903543 IMP involved_in positive regulation of exosomal secretion 22660413,24105262 Process
7251 GO:1903551 IMP involved_in regulation of extracellular exosome assembly 24105262 Process
7251 GO:1903774 IMP involved_in positive regulation of viral budding via host ESCRT complex 11595185,15218037 Process