Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:7412
  • Symbol:VCAM1
  • Description:vascular cell adhesion molecule 1

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7412 GO:0002102 IDA located_in podosome 15220135 Component
7412 GO:0005615 IDA located_in extracellular space 9290466 Component
7412 GO:0005769 IDA located_in early endosome 23474851 Component
7412 GO:0005783 IDA located_in endoplasmic reticulum 23474851 Component
7412 GO:0005794 IDA located_in Golgi apparatus 23474851 Component
7412 GO:0005902 IDA located_in microvillus 12082081 Component
7412 GO:0009897 IDA located_in external side of plasma membrane 1377228 Component
7412 GO:0009986 IDA located_in cell surface 1715889,23474851 Component
7412 GO:0030175 IDA located_in filopodium 12082081 Component
7412 GO:0045177 IDA located_in apical part of cell 12082081 Component
7412 GO:0070062 HDA located_in extracellular exosome 23533145 Component
7412 GO:0071065 IDA part_of alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex 15220135 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7412 GO:0005178 IDA enables integrin binding 1377228,15220135,23620790 Function
7412 GO:0005178 IMP enables integrin binding 19738201 Function
7412 GO:0008131 IDA enables primary amine oxidase activity 23474851 Function
7412 GO:0050839 IDA enables cell adhesion molecule binding 1377228 Function
7412 GO:0050839 IPI enables cell adhesion molecule binding 12082081 Function
7412 GO:0098631 IDA enables cell adhesion mediator activity 22970700 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7412 GO:0006954 IDA involved_in inflammatory response 22970700 Process
7412 GO:0007155 IDA involved_in cell adhesion 16809613 Process
7412 GO:0007157 IDA involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 1715889 Process
7412 GO:0007159 IDA involved_in leukocyte cell-cell adhesion 1381355,1715889,2688898 Process
7412 GO:0007160 IDA involved_in cell-matrix adhesion 18308860 Process
7412 GO:0009308 IDA involved_in amine metabolic process 23474851 Process
7412 GO:0022614 IEP involved_in membrane to membrane docking 12082081 Process
7412 GO:0034113 IGI involved_in heterotypic cell-cell adhesion 11078691 Process
7412 GO:0035584 IGI involved_in calcium-mediated signaling using intracellular calcium source 15879141 Process
7412 GO:0042102 IDA involved_in positive regulation of T cell proliferation 1381355 Process
7412 GO:0050901 IDA involved_in leukocyte tethering or rolling 18308860 Process
7412 GO:0050901 IEP involved_in leukocyte tethering or rolling 2688898 Process
7412 GO:0140039 IGI involved_in cell-cell adhesion in response to extracellular stimulus 11078691 Process
7412 GO:1904646 IGI involved_in cellular response to amyloid-beta 11078691 Process