Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:7430
  • Symbol:EZR
  • Description:ezrin

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7430 GO:0000122 IMP involved_in negative regulation of transcription by RNA polymerase II 20551903 Process
7430 GO:0003376 IMP involved_in sphingosine-1-phosphate receptor signaling pathway 23106337 Process
7430 GO:0007159 IEP involved_in leukocyte cell-cell adhesion 12082081 Process
7430 GO:0008360 IMP involved_in regulation of cell shape 20551903 Process
7430 GO:0008361 IMP NOT involved_in regulation of cell size 22467863 Process
7430 GO:0010628 IGI involved_in positive regulation of gene expression 23264465 Process
7430 GO:0010737 IMP involved_in protein kinase A signaling 17911601 Process
7430 GO:0022612 IMP NOT involved_in gland morphogenesis 24862762 Process
7430 GO:0022614 IEP involved_in membrane to membrane docking 12082081 Process
7430 GO:0030033 IMP involved_in microvillus assembly 22797597 Process
7430 GO:0030036 IMP involved_in actin cytoskeleton organization 23106337 Process
7430 GO:0030953 IMP involved_in astral microtubule organization 20551903 Process
7430 GO:0031503 IMP involved_in protein-containing complex localization 20551903 Process
7430 GO:0032703 IMP involved_in negative regulation of interleukin-2 production 17911601 Process
7430 GO:0032956 IMP NOT involved_in regulation of actin cytoskeleton organization 20551903 Process
7430 GO:0043622 IMP involved_in cortical microtubule organization 20551903 Process
7430 GO:0045198 IMP NOT involved_in establishment of epithelial cell apical/basal polarity 22797597,24862762 Process
7430 GO:0045732 IGI involved_in positive regulation of protein catabolic process 21148287 Process
7430 GO:0046847 IMP involved_in filopodium assembly 23106337 Process
7430 GO:0048015 IDA involved_in phosphatidylinositol-mediated signaling Process
7430 GO:0050714 IMP involved_in positive regulation of protein secretion Process
7430 GO:0050860 IMP involved_in negative regulation of T cell receptor signaling pathway 20551903 Process
7430 GO:0051017 IDA involved_in actin filament bundle assembly 10793131 Process
7430 GO:0051660 IMP involved_in establishment of centrosome localization 20551903 Process
7430 GO:0061028 IGI involved_in establishment of endothelial barrier 23264465 Process
7430 GO:0070373 IMP involved_in negative regulation of ERK1 and ERK2 cascade 20551903 Process
7430 GO:0071320 IMP involved_in cellular response to cAMP 17911601 Process
7430 GO:0072659 IMP involved_in protein localization to plasma membrane 17825285,17911601 Process
7430 GO:0072697 IMP involved_in protein localization to cell cortex 25554515 Process
7430 GO:1901222 IMP NOT involved_in regulation of NIK/NF-kappaB signaling 20551903 Process
7430 GO:1902115 IGI involved_in regulation of organelle assembly 21148287 Process
7430 GO:1902115 IMP involved_in regulation of organelle assembly 21148287 Process
7430 GO:1902966 IGI involved_in positive regulation of protein localization to early endosome 21148287 Process
7430 GO:1903753 IMP involved_in negative regulation of p38MAPK cascade 20551903 Process
7430 GO:2000643 IGI involved_in positive regulation of early endosome to late endosome transport 21148287 Process
7430 GO:2000643 IMP involved_in positive regulation of early endosome to late endosome transport 21148287 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7430 GO:0001650 IDA located_in fibrillar center Component
7430 GO:0001726 IDA located_in ruffle 9852149,25554515 Component
7430 GO:0001772 IDA colocalizes_with immunological synapse 17911601 Component
7430 GO:0001772 IDA located_in immunological synapse 20551903 Component
7430 GO:0005615 HDA located_in extracellular space 16502470 Component
7430 GO:0005737 IDA located_in cytoplasm 23106337,25554515 Component
7430 GO:0005768 IDA located_in endosome 21148287 Component
7430 GO:0005829 IDA located_in cytosol 9852149 Component
7430 GO:0005884 IDA located_in actin filament 11598191 Component
7430 GO:0005886 IDA located_in plasma membrane 7844168,23106337 Component
7430 GO:0005902 IDA located_in microvillus 12082081 Component
7430 GO:0005925 HDA located_in focal adhesion 21423176 Component
7430 GO:0005925 IDA colocalizes_with focal adhesion 21282464 Component
7430 GO:0015629 IDA located_in actin cytoskeleton 10793131 Component
7430 GO:0016020 HDA located_in membrane 19946888 Component
7430 GO:0016324 IDA located_in apical plasma membrane 17825285,22797597,24862762 Component
7430 GO:0030175 IDA located_in filopodium 12082081,23106337 Component
7430 GO:0031982 HDA located_in vesicle 19190083 Component
7430 GO:0032991 IDA part_of protein-containing complex 25097019 Component
7430 GO:0042995 IDA located_in cell projection 25889165 Component
7430 GO:0044853 IDA located_in plasma membrane raft 17911601 Component
7430 GO:0045177 IDA located_in apical part of cell 12082081 Component
7430 GO:0048471 IDA located_in perinuclear region of cytoplasm 24862762 Component
7430 GO:0070062 HDA located_in extracellular exosome 20458337,23533145 Component
7430 GO:0071944 IDA located_in cell periphery 22291017 Component
7430 GO:0098592 IDA located_in cytoplasmic side of apical plasma membrane Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7430 GO:0003723 HDA enables RNA binding 22658674,22681889 Function
7430 GO:0003779 IDA enables actin binding 17825285 Function
7430 GO:0005515 IPI enables protein binding 7844168,10793131,10806479,11598191,12651155,15020681,15498789,..... Function
7430 GO:0008017 IMP enables microtubule binding 23857773 Function
7430 GO:0019904 IPI enables protein domain specific binding 25554515 Function
7430 GO:0034236 IPI enables protein kinase A catalytic subunit binding 17911601 Function
7430 GO:0034237 IPI enables protein kinase A regulatory subunit binding 17911601 Function
7430 GO:0042802 IPI enables identical protein binding 21988832,29568061,31837246 Function
7430 GO:0044548 IPI enables S100 protein binding 25554515 Function
7430 GO:0045296 HDA enables cadherin binding 25468996 Function
7430 GO:0050839 IPI enables cell adhesion molecule binding 12082081,15498789 Function
7430 GO:0051015 IDA enables actin filament binding 10793131 Function
7430 GO:0051018 IPI enables protein kinase A binding 25097019 Function
7430 GO:0051117 IPI enables ATPase binding 17825285 Function