Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:775
  • Symbol:CACNA1C
  • Description:calcium voltage-gated channel subunit alpha1 C

Process

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
775 GO:0002520 IMP involved_in immune system development 15454078 Process
775 GO:0007204 IDA involved_in positive regulation of cytosolic calcium ion concentration 12130699 Process
775 GO:0007507 IMP involved_in heart development 15454078 Process
775 GO:0035115 IMP involved_in embryonic forelimb morphogenesis 15454078 Process
775 GO:0043010 IMP involved_in camera-type eye development 15454078 Process
775 GO:0061337 IMP involved_in cardiac conduction 24728418 Process
775 GO:0061577 IDA involved_in calcium ion transmembrane transport via high voltage-gated calcium channel 15454078 Process
775 GO:0061577 IMP involved_in calcium ion transmembrane transport via high voltage-gated calcium channel 30023270,30172029,30513141,34163037 Process
775 GO:0070588 IDA involved_in calcium ion transmembrane transport 15454078 Process
775 GO:0070588 IMP involved_in calcium ion transmembrane transport 24728418 Process
775 GO:0086002 IMP involved_in cardiac muscle cell action potential involved in contraction 15454078 Process
775 GO:0086012 IMP involved_in membrane depolarization during cardiac muscle cell action potential 15454078 Process
775 GO:0086045 IMP involved_in membrane depolarization during AV node cell action potential 26253506 Process
775 GO:0086091 IMP involved_in regulation of heart rate by cardiac conduction 15454078,15863612,17224476,26253506 Process
775 GO:0098911 IMP involved_in regulation of ventricular cardiac muscle cell action potential 15454078,26253506 Process
775 GO:0098912 IMP involved_in membrane depolarization during atrial cardiac muscle cell action potential 17224476 Process

Function

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
775 GO:0005245 IDA enables voltage-gated calcium channel activity 8392192,12130699 Function
775 GO:0005245 IMP enables voltage-gated calcium channel activity 24728418 Function
775 GO:0005515 IPI enables protein binding 11438518,15140941,18535142,21653829 Function
775 GO:0005516 IPI enables calmodulin binding 15140941 Function
775 GO:0008331 IDA enables high voltage-gated calcium channel activity 15454078 Function
775 GO:0051393 IPI enables alpha-actinin binding 17110593 Function
775 GO:0086007 IMP contributes_to voltage-gated calcium channel activity involved in cardiac muscle cell action potential 17224476 Function
775 GO:0086007 IMP enables voltage-gated calcium channel activity involved in cardiac muscle cell action potential 15454078 Function
775 GO:0086056 IMP enables voltage-gated calcium channel activity involved in AV node cell action potential 26253506 Function

Component

Export (tab separated) Export to Excel
GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
775 GO:0005737 IDA located_in cytoplasm 11206130 Component
775 GO:0005886 IDA located_in plasma membrane 11206130 Component
775 GO:0005891 IDA part_of voltage-gated calcium channel complex 12130699,17224476 Component
775 GO:0014069 IDA located_in postsynaptic density 14140941 Component
775 GO:0016020 IDA located_in membrane 8392192 Component
775 GO:1990454 IDA part_of L-type voltage-gated calcium channel complex 15454078 Component