Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:7879
  • Symbol:RAB7A
  • Description:RAB7A, member RAS oncogene family

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7879 GO:0000045 IMP involved_in autophagosome assembly 19956673 Process
7879 GO:0006622 IMP involved_in protein targeting to lysosome 22115783 Process
7879 GO:0007174 IMP involved_in epidermal growth factor catabolic process 18272684 Process
7879 GO:0008333 IMP involved_in endosome to lysosome transport 18272684 Process
7879 GO:0009617 IMP involved_in response to bacterium 22042847 Process
7879 GO:0019076 IMP involved_in viral release from host cell 22072966 Process
7879 GO:0022615 IDA involved_in protein to membrane docking 24344282 Process
7879 GO:0042147 IMP involved_in retrograde transport, endosome to Golgi 19531583 Process
7879 GO:0045022 IMP involved_in early endosome to late endosome transport 14617358 Process
7879 GO:0045732 IMP involved_in positive regulation of protein catabolic process 22072966 Process
7879 GO:0046907 IMP involved_in intracellular transport 22042847 Process
7879 GO:0048524 IMP involved_in positive regulation of viral process 22072966 Process
7879 GO:0090383 IMP involved_in phagosome acidification 21255211 Process
7879 GO:0090385 IMP involved_in phagosome-lysosome fusion 21255211 Process
7879 GO:0099638 IMP involved_in endosome to plasma membrane protein transport 33147445 Process
7879 GO:1903542 IMP involved_in negative regulation of exosomal secretion 26911690 Process
7879 GO:1903543 IMP involved_in positive regulation of exosomal secretion 22660413 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7879 GO:0003924 IDA enables GTPase activity 18272684 Function
7879 GO:0005515 IPI enables protein binding 14617358,15471887,15933719,16176980,16925951,18272684,18787122..... Function
7879 GO:0005525 IDA enables GTP binding 18272684 Function
7879 GO:0019003 IDA enables GDP binding 18272684 Function
7879 GO:1905394 IMP enables retromer complex binding 27385586 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7879 GO:0005739 IDA located_in mitochondrion 34432599 Component
7879 GO:0005764 IDA colocalizes_with lysosome 18272684 Component
7879 GO:0005764 IDA located_in lysosome 15078902 Component
7879 GO:0005770 IDA colocalizes_with late endosome 18272684 Component
7879 GO:0005770 IDA located_in late endosome 14617358,15078902,17010938 Component
7879 GO:0010008 IDA located_in endosome membrane 22431521 Component
7879 GO:0010008 IMP located_in endosome membrane 26911690 Component
7879 GO:0045335 IDA located_in phagocytic vesicle 21255211 Component
7879 GO:0070062 HDA located_in extracellular exosome 19056867,20458337,23533145 Component