Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:7917
  • Symbol:BAG6
  • Description:BAG cochaperone 6

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7917 GO:0002429 IDA involved_in immune response-activating cell surface receptor signaling pathway 18852879 Process
7917 GO:0006511 IDA involved_in ubiquitin-dependent protein catabolic process 20676083 Process
7917 GO:0006620 IDA involved_in post-translational protein targeting to endoplasmic reticulum membrane 25535373 Process
7917 GO:0006915 IDA involved_in apoptotic process 14960581 Process
7917 GO:0010498 IMP involved_in proteasomal protein catabolic process 26565908 Process
7917 GO:0018393 IDA involved_in internal peptidyl-lysine acetylation 17403783 Process
7917 GO:0030101 IDA involved_in natural killer cell activation 18852879 Process
7917 GO:0030433 IDA involved_in ubiquitin-dependent ERAD pathway 23129660,24981174 Process
7917 GO:0030433 IMP involved_in ubiquitin-dependent ERAD pathway 26565908 Process
7917 GO:0031647 IDA involved_in regulation of protein stability 21636303 Process
7917 GO:0042771 IMP involved_in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 17403783 Process
7917 GO:0061857 IMP involved_in endoplasmic reticulum stress-induced pre-emptive quality control 26565908 Process
7917 GO:0071712 IDA involved_in ER-associated misfolded protein catabolic process 23129660,24981174 Process
7917 GO:0071816 IDA involved_in tail-anchored membrane protein insertion into ER membrane 20676083,25535373 Process
7917 GO:1904294 IMP involved_in positive regulation of ERAD pathway 24424410 Process
7917 GO:1904378 IMP involved_in maintenance of unfolded protein involved in ERAD pathway 21636303 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7917 GO:0005102 IPI enables signaling receptor binding 18852879 Function
7917 GO:0005515 IPI enables protein binding 14667819,14960581,16189514,17403783,18765639,18852879,21903422..... Function
7917 GO:0031625 IPI enables ubiquitin protein ligase binding 21636303,24981174 Function
7917 GO:0043022 IDA enables ribosome binding 20676083 Function
7917 GO:0051787 IDA enables misfolded protein binding 21636303 Function
7917 GO:1990381 IPI enables ubiquitin-specific protease binding 24424410 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7917 GO:0005634 IDA located_in nucleus 14960581,17403783,21636303,29042515 Component
7917 GO:0005654 IDA located_in nucleoplasm Component
7917 GO:0005737 IDA located_in cytoplasm 21636303 Component
7917 GO:0005829 IDA located_in cytosol 17403783,20676083,23246001,29042515 Component
7917 GO:0016020 HDA located_in membrane 19946888 Component
7917 GO:0016020 IDA located_in membrane 23246001 Component
7917 GO:0043231 IDA located_in intracellular membrane-bounded organelle Component
7917 GO:0070062 IDA located_in extracellular exosome 18852879 Component
7917 GO:0071818 IDA part_of BAT3 complex 20676083,21636303,25535373 Component
7917 GO:0071818 IPI part_of BAT3 complex 25535373 Component