Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:7942
  • Symbol:TFEB
  • Description:transcription factor EB

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7942 GO:0000976 IDA enables transcription cis-regulatory region binding 19556463 Function
7942 GO:0003700 IDA enables DNA-binding transcription factor activity 19556463,21617040,22343943,22576015,22692423,25720963,32753672..... Function
7942 GO:0005515 IPI enables protein binding 22343943 Function
7942 GO:0019899 IPI enables enzyme binding 22576015,22692423 Function
7942 GO:1990837 IDA enables sequence-specific double-stranded DNA binding 28473536 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7942 GO:0005634 IDA is_active_in nucleus 25720963,32753672,35662396 Component
7942 GO:0005634 IDA located_in nucleus 19556463,21617040,22343943,22576015,22692423,27278822..... Component
7942 GO:0005737 IDA located_in cytoplasm 19556463,27278822 Component
7942 GO:0005765 IDA located_in lysosomal membrane 22343943,22692423 Component
7942 GO:0005829 IDA located_in cytosol 21617040,22576015,25720963,32753672,35662396 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
7942 GO:0007040 IDA involved_in lysosome organization 22692423,32753672,35662396 Process
7942 GO:0007040 IMP involved_in lysosome organization 23434374 Process
7942 GO:0009267 IDA involved_in cellular response to starvation 21617040,22343943,22576015,22692423 Process
7942 GO:0010508 IDA involved_in positive regulation of autophagy 21617040,22576015 Process
7942 GO:0010508 IMP involved_in positive regulation of autophagy 23434374 Process
7942 GO:0032418 IMP involved_in lysosome localization 29146937 Process
7942 GO:0034198 IDA involved_in cellular response to amino acid starvation 22343943,22576015,22692423 Process
7942 GO:0045893 IDA involved_in positive regulation of DNA-templated transcription 21617040,22343943,22576015,22692423,27278822,29146937..... Process
7942 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 19556463 Process
7942 GO:0140367 IDA involved_in antibacterial innate immune response 32753672,35662396 Process