Gene Ontology

Gene Info

  • Species:Rat (Rattus norvegicus)
  • GeneID:84027
  • Symbol:Gsk3b
  • Description:glycogen synthase kinase 3 beta

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
84027 GO:0004674 IDA enables protein serine/threonine kinase activity 2164470,9482734,11035810,16879317,17329210 Function
84027 GO:0005178 IPI enables integrin binding 18677563 Function
84027 GO:0005515 IPI enables protein binding 9482734,10228155,12610628,17728459,19318234 Function
84027 GO:0005524 IDA enables ATP binding 16879317,17329210 Function
84027 GO:0016301 IDA enables kinase activity 1346104 Function
84027 GO:0019901 IPI enables protein kinase binding 16478782,20841359 Function
84027 GO:0035255 IPI enables ionotropic glutamate receptor binding 17329210 Function
84027 GO:0048156 IDA enables tau protein binding 16735023 Function
84027 GO:0050321 IDA enables tau-protein kinase activity 16735023 Function
84027 GO:0120283 IPI enables protein serine/threonine kinase binding 8524413 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
84027 GO:0005874 IDA located_in microtubule 8576078 Component
84027 GO:0016020 IDA located_in membrane 16815997 Component
84027 GO:0030424 IDA located_in axon 15652487 Component
84027 GO:0030425 IDA located_in dendrite 15652487 Component
84027 GO:0030877 IDA part_of beta-catenin destruction complex 10228155 Component
84027 GO:0032991 IDA part_of protein-containing complex 17329210 Component
84027 GO:0043197 IDA located_in dendritic spine 17329210 Component
84027 GO:0098685 IDA is_active_in Schaffer collateral - CA1 synapse 23864697 Component
84027 GO:0098685 IMP is_active_in Schaffer collateral - CA1 synapse 23864697 Component
84027 GO:0098978 IDA is_active_in glutamatergic synapse 23864697 Component
84027 GO:0098978 IMP is_active_in glutamatergic synapse 23864697 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
84027 GO:0006468 IDA involved_in protein phosphorylation 11035810,16879317,17329210 Process
84027 GO:0007163 IDA involved_in establishment or maintenance of cell polarity 12610628 Process
84027 GO:0009410 IEP involved_in response to xenobiotic stimulus 19359144 Process
84027 GO:0010043 IDA involved_in response to zinc ion 27295130 Process
84027 GO:0010918 IMP involved_in positive regulation of mitochondrial membrane potential 19318234 Process
84027 GO:0014823 IEP involved_in response to activity 22252247 Process
84027 GO:0030010 IDA involved_in establishment of cell polarity 12610628 Process
84027 GO:0030010 IMP involved_in establishment of cell polarity 15652487 Process
84027 GO:0030011 IMP involved_in maintenance of cell polarity 15652487 Process
84027 GO:0030516 IMP involved_in regulation of axon extension 15652487 Process
84027 GO:0032355 IEP involved_in response to estradiol 22252247 Process
84027 GO:0032868 IEP involved_in response to insulin 16934435 Process
84027 GO:0033690 IMP involved_in positive regulation of osteoblast proliferation 26722385 Process
84027 GO:0034392 IMP involved_in negative regulation of smooth muscle cell apoptotic process 21557011 Process
84027 GO:0035733 IMP involved_in hepatic stellate cell activation 28061416 Process
84027 GO:0036018 IEP involved_in cellular response to erythropoietin 17952604 Process
84027 GO:0043065 IDA involved_in positive regulation of apoptotic process 12393899 Process
84027 GO:0043065 IMP involved_in positive regulation of apoptotic process 12808104 Process
84027 GO:0043407 IMP involved_in negative regulation of MAP kinase activity 17182785 Process
84027 GO:0043525 IMP involved_in positive regulation of neuron apoptotic process 16765055,20841359 Process
84027 GO:0045667 IMP involved_in regulation of osteoblast differentiation 28731198 Process
84027 GO:0045672 IMP involved_in positive regulation of osteoclast differentiation 28731198 Process
84027 GO:0045732 IMP involved_in positive regulation of protein catabolic process 17686886 Process
84027 GO:0045886 IMP involved_in negative regulation of synaptic assembly at neuromuscular junction 25764078 Process
84027 GO:0045887 IMP involved_in positive regulation of synaptic assembly at neuromuscular junction 25764078 Process
84027 GO:0046627 IDA involved_in negative regulation of insulin receptor signaling pathway 8524413 Process
84027 GO:0046849 IDA involved_in bone remodeling 29224185 Process
84027 GO:0048168 IMP involved_in regulation of neuronal synaptic plasticity 17329210 Process
84027 GO:0048661 IMP involved_in positive regulation of smooth muscle cell proliferation 21557011 Process
84027 GO:0048814 IMP involved_in regulation of dendrite morphogenesis 15652487 Process
84027 GO:0050770 IMP involved_in regulation of axonogenesis 15652487 Process
84027 GO:0050774 IMP involved_in negative regulation of dendrite morphogenesis 17182785 Process
84027 GO:0051001 IMP involved_in negative regulation of nitric-oxide synthase activity 18005341 Process
84027 GO:0061049 IDA involved_in cell growth involved in cardiac muscle cell development 27854077 Process
84027 GO:0070301 IEP involved_in cellular response to hydrogen peroxide 18005341 Process
84027 GO:0070507 IMP involved_in regulation of microtubule cytoskeleton organization 18268107 Process
84027 GO:0071260 IDA involved_in cellular response to mechanical stimulus 20042609 Process
84027 GO:0071282 IEP involved_in cellular response to iron(II) ion 19608791 Process
84027 GO:0071285 IEP involved_in cellular response to lithium ion 18932008 Process
84027 GO:0071871 IEP involved_in response to epinephrine 16934435 Process
84027 GO:0090290 IMP involved_in positive regulation of osteoclast proliferation 26722385 Process
84027 GO:0097284 IDA involved_in hepatocyte apoptotic process 28638224 Process
84027 GO:0098696 IDA involved_in regulation of neurotransmitter receptor localization to postsynaptic specialization membrane 23864697 Process
84027 GO:0098696 IMP involved_in regulation of neurotransmitter receptor localization to postsynaptic specialization membrane 23864697 Process
84027 GO:0099159 IDA involved_in regulation of modification of postsynaptic structure 23864697 Process
84027 GO:0099159 IMP involved_in regulation of modification of postsynaptic structure 23864697 Process
84027 GO:0106027 IMP involved_in neuron projection organization 15652487 Process
84027 GO:1900181 IMP involved_in negative regulation of protein localization to nucleus 23624080 Process
84027 GO:1901984 IMP involved_in negative regulation of protein acetylation 18268107 Process
84027 GO:1902065 IEP involved_in response to L-glutamate 18445133 Process
84027 GO:1903351 IEP involved_in cellular response to dopamine 20007479 Process
84027 GO:1904339 IMP involved_in negative regulation of dopaminergic neuron differentiation 15522889 Process
84027 GO:1904646 IDA involved_in cellular response to amyloid-beta 26224839 Process
84027 GO:1990418 IEP involved_in response to insulin-like growth factor stimulus 17686886 Process
84027 GO:1990478 IEP involved_in response to ultrasound 20708505 Process
84027 GO:1990776 IEP involved_in response to angiotensin 22982863 Process
84027 GO:2000171 IMP involved_in negative regulation of dendrite development 23470087 Process
84027 GO:2000463 IMP involved_in positive regulation of excitatory postsynaptic potential 20007479 Process
84027 GO:2000573 IMP involved_in positive regulation of DNA biosynthetic process 12721208 Process
84027 GO:2001223 IMP involved_in negative regulation of neuron migration 11403684 Process