Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:842
• Symbol:CASP9
• Description:caspase 9

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
842	GO:0004197	IDA	enables	cysteine-type endopeptidase activity	16920334	Function
842	GO:0005515	IPI	enables	protein binding	9922454,10206961,10376594,11024045,11069302,11084335,11350957,.....	Function
842	GO:0008233	IDA	enables	peptidase activity	19740745	Function
842	GO:0017124	IDA	enables	SH3 domain binding	15657060	Function
842	GO:0019901	IDA	enables	protein kinase binding	15657060	Function
842	GO:0097153	IDA	enables	cysteine-type endopeptidase activity involved in apoptotic process	16352606,16916640,27889207	Function
842	GO:0097199	IDA	enables	cysteine-type endopeptidase activity involved in apoptotic signaling pathway	16916640,16920334	Function
842	GO:0097199	IMP	enables	cysteine-type endopeptidase activity involved in apoptotic signaling pathway	21980415	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
842	GO:0005739	IDA	is_active_in	mitochondrion	12782307	Component
842	GO:0005829	IDA	located_in	cytosol	17167422	Component
842	GO:0008303	IPI	part_of	caspase complex	11734640	Component
842	GO:0032991	IDA	part_of	protein-containing complex	11821383	Component
842	GO:0043293	IDA	part_of	apoptosome	21827945	Component
842	GO:0043293	IPI	part_of	apoptosome	10206961	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
842	GO:0006915	IMP	involved_in	apoptotic process	15069058	Process
842	GO:0006919	IDA	involved_in	activation of cysteine-type endopeptidase activity involved in apoptotic process	16916640	Process
842	GO:0006974	IDA	involved_in	DNA damage response	15657060	Process
842	GO:0006974	IMP	involved_in	DNA damage response	15657060	Process
842	GO:0008630	IMP	involved_in	intrinsic apoptotic signaling pathway in response to DNA damage	15657060	Process
842	GO:0008635	IDA	involved_in	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c	10206961	Process
842	GO:0034644	IDA	involved_in	cellular response to UV	15657060	Process
842	GO:0042770	IDA	involved_in	signal transduction in response to DNA damage	15657060	Process
842	GO:0043065	IMP	involved_in	positive regulation of apoptotic process	11821383	Process
842	GO:0051604	IDA	involved_in	protein maturation	16352606,16916640	Process
842	GO:0097193	IDA	involved_in	intrinsic apoptotic signaling pathway	35446120	Process
842	GO:0097202	IDA	involved_in	activation of cysteine-type endopeptidase activity	10206961,27882936	Process