Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:8717
  • Symbol:TRADD
  • Description:TNFRSF1A associated via death domain

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
8717 GO:0002947 IDA part_of tumor necrosis factor receptor superfamily complex 23429285 Component
8717 GO:0005737 IDA located_in cytoplasm 11684708,22510408 Component
8717 GO:0005886 IDA located_in plasma membrane 22510408 Component
8717 GO:0043235 IDA part_of receptor complex 8612133 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
8717 GO:0005068 IPI enables transmembrane receptor protein tyrosine kinase adaptor activity 8612133 Function
8717 GO:0005515 IPI enables protein binding 1040062,7758105,8565075,8943045,8985253,9020361,10848577,10892..... Function
8717 GO:0019900 IPI enables kinase binding 8612133 Function
8717 GO:0042802 IPI enables identical protein binding 7758105,11684708,30561431 Function
8717 GO:0060090 IDA enables molecular adaptor activity 7758105 Function
8717 GO:0070513 IPI enables death domain binding 8612133 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
8717 GO:0030335 IMP involved_in positive regulation of cell migration 25732226 Process
8717 GO:0033209 IDA involved_in tumor necrosis factor-mediated signaling pathway 7758105 Process
8717 GO:0043123 IEP involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling 12761501 Process
8717 GO:0050729 IMP involved_in positive regulation of inflammatory response 25732226 Process
8717 GO:0051092 IMP involved_in positive regulation of NF-kappaB transcription factor activity 25732226 Process
8717 GO:0071356 IMP involved_in cellular response to tumor necrosis factor 25732226 Process
8717 GO:0097191 IMP involved_in extrinsic apoptotic signaling pathway 16611992 Process
8717 GO:1901224 IMP involved_in positive regulation of NIK/NF-kappaB signaling 25732226 Process