Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:8841
  • Symbol:HDAC3
  • Description:histone deacetylase 3

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
8841 GO:0000118 IDA part_of histone deacetylase complex 18326024 Component
8841 GO:0005634 IDA located_in nucleus 18326024,18347167,21030595 Component
8841 GO:0005654 IDA located_in nucleoplasm Component
8841 GO:0005737 IDA located_in cytoplasm 25190803 Component
8841 GO:0005794 IDA located_in Golgi apparatus Component
8841 GO:0005829 IDA located_in cytosol 21030595 Component
8841 GO:0005886 IDA located_in plasma membrane Component
8841 GO:0017053 IDA part_of transcription repressor complex 11804585,12628926,16569215,18417529 Component
8841 GO:0072686 IDA located_in mitotic spindle 18326024 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
8841 GO:0000122 IDA involved_in negative regulation of transcription by RNA polymerase II 16569215,18417529,18854353 Process
8841 GO:0000122 IMP involved_in negative regulation of transcription by RNA polymerase II 12628926 Process
8841 GO:0000132 IDA involved_in establishment of mitotic spindle orientation 34608293 Process
8841 GO:0001934 IDA involved_in positive regulation of protein phosphorylation 25190803 Process
8841 GO:0006476 IDA involved_in protein deacetylation 21030595,25301942 Process
8841 GO:0010832 IMP NOT involved_in negative regulation of myotube differentiation 10983972 Process
8841 GO:0031647 IDA involved_in regulation of protein stability 25190803 Process
8841 GO:0032008 IMP involved_in positive regulation of TOR signaling 25190803 Process
8841 GO:0042307 IDA involved_in positive regulation of protein import into nucleus 25190803 Process
8841 GO:0045892 IMP involved_in negative regulation of DNA-templated transcription 16924111 Process
8841 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 25190803 Process
8841 GO:0046329 IMP involved_in negative regulation of JNK cascade 11931768 Process
8841 GO:0051225 IMP involved_in spindle assembly 18326024 Process
8841 GO:0071498 IDA involved_in cellular response to fluid shear stress 25190803 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
8841 GO:0001222 IPI enables transcription corepressor binding 10898795,12535528 Function
8841 GO:0003682 IDA enables chromatin binding 16569215,18417529 Function
8841 GO:0003714 IDA enables transcription corepressor activity 16569215,18417529 Function
8841 GO:0003714 IMP enables transcription corepressor activity 12628926 Function
8841 GO:0004407 IDA enables histone deacetylase activity 28497810 Function
8841 GO:0004407 IMP enables histone deacetylase activity 16924111,18326024 Function
8841 GO:0005515 IPI enables protein binding 11006275,11013263,11259576,11641274,11861901,15016912,15194749..... Function
8841 GO:0019899 IPI enables enzyme binding 11641274 Function
8841 GO:0030332 IPI enables cyclin binding 18417529 Function
8841 GO:0033558 IDA enables protein lysine deacetylase activity 17172643,25301942 Function
8841 GO:0042826 IPI enables histone deacetylase binding 10869435,12590135,23867755 Function
8841 GO:0051059 IPI enables NF-kappaB binding 17785205 Function
8841 GO:0160008 IDA enables protein decrotonylase activity 34608293 Function
8841 GO:0160009 IDA enables histone decrotonylase activity 28497810 Function
8841 GO:0160010 IDA enables protein de-2-hydroxyisobutyrylase activity 29192674 Function