Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:8874
  • Symbol:ARHGEF7
  • Description:Rho guanine nucleotide exchange factor 7

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
8874 GO:0005085 EXP enables guanyl-nucleotide exchange factor activity 12695502,17310244 Function
8874 GO:0005085 IDA enables guanyl-nucleotide exchange factor activity 21048939 Function
8874 GO:0005515 IPI enables protein binding 11864573,15182672,16101281,16374509,16407834,16492808,16628223..... Function
8874 GO:0019901 IPI enables protein kinase binding 21048939 Function
8874 GO:0043015 IDA enables gamma-tubulin binding 27012601 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
8874 GO:0005813 IDA located_in centrosome 27012601 Component
8874 GO:0005925 HDA located_in focal adhesion 21423176 Component
8874 GO:0032991 IDA part_of protein-containing complex 11864573 Component
8874 GO:0043005 IDA located_in neuron projection 21048939 Component
8874 GO:0043025 IDA located_in neuronal cell body 21048939 Component
8874 GO:0097431 IDA located_in mitotic spindle pole 27012601 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
8874 GO:0007030 IMP involved_in Golgi organization 25500533 Process
8874 GO:0010763 HDA involved_in positive regulation of fibroblast migration 21423176 Process
8874 GO:0043065 IMP involved_in positive regulation of apoptotic process 19041750 Process
8874 GO:0043547 HMP involved_in positive regulation of GTPase activity 21423176 Process
8874 GO:0043547 IDA involved_in positive regulation of GTPase activity 21048939 Process
8874 GO:0048041 HDA involved_in focal adhesion assembly 21423176 Process
8874 GO:1900026 HMP involved_in positive regulation of substrate adhesion-dependent cell spreading 21423176 Process
8874 GO:1904424 IMP involved_in regulation of GTP binding 25500533 Process
8874 GO:1905833 IMP involved_in negative regulation of microtubule nucleation 27012601 Process
8874 GO:2000394 HMP involved_in positive regulation of lamellipodium morphogenesis 21423176 Process