Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:9448
• Symbol:MAP4K4
• Description:mitogen-activated protein kinase kinase kinase kinase 4

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
9448	GO:0004111	IDA	enables	creatine kinase activity	23207904	Function
9448	GO:0004674	IDA	enables	protein serine/threonine kinase activity	9890973	Function
9448	GO:0005515	IPI	enables	protein binding	12387898,14966141,25852190,29961565,32707033	Function
9448	GO:0005524	IDA	enables	ATP binding	9890973	Function
9448	GO:0008017	IDA	enables	microtubule binding	25490267	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
9448	GO:0005737	IDA	located_in	cytoplasm	14966141	Component
9448	GO:0005925	IDA	located_in	focal adhesion	25490267	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
9448	GO:0006468	IDA	involved_in	protein phosphorylation	9890973	Process
9448	GO:0030033	IMP	NOT involved_in	microvillus assembly	22797597	Process
9448	GO:0030335	IMP	involved_in	positive regulation of cell migration	24163766	Process
9448	GO:0035556	IDA	involved_in	intracellular signal transduction	9890973	Process
9448	GO:0043066	IMP	involved_in	negative regulation of apoptotic process	21196414	Process
9448	GO:0046328	IDA	involved_in	regulation of JNK cascade	14966141	Process