Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:9525
  • Symbol:VPS4B
  • Description:vacuolar protein sorting 4 homolog B

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
9525 GO:0000922 IDA located_in spindle pole 20616062 Component
9525 GO:0005634 IDA located_in nucleus 16757520,20616062 Component
9525 GO:0005737 IDA located_in cytoplasm 16757520,20616062 Component
9525 GO:0005768 IDA located_in endosome 11563910 Component
9525 GO:0005813 IDA located_in centrosome 20616062 Component
9525 GO:0010008 IDA located_in endosome membrane 16757520 Component
9525 GO:0070062 HDA located_in extracellular exosome 19056867,23533145 Component
9525 GO:0090543 IDA located_in Flemming body 20616062 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
9525 GO:0005515 IPI enables protein binding 11563910,14505570,16193069,16757520,17928862,18385515,18687924..... Function
9525 GO:0016887 IDA enables ATP hydrolysis activity 11563910,18687924 Function
9525 GO:0042802 IDA enables identical protein binding 16193069 Function
9525 GO:0042803 IDA enables protein homodimerization activity 16193069 Function
9525 GO:0044877 IDA enables protein-containing complex binding 18687924 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
9525 GO:0006997 IMP involved_in nucleus organization 20616062 Process
9525 GO:0007080 IMP involved_in mitotic metaphase plate congression 20616062 Process
9525 GO:0010824 IMP involved_in regulation of centrosome duplication 20616062 Process
9525 GO:0010971 IMP involved_in positive regulation of G2/M transition of mitotic cell cycle 20616062 Process
9525 GO:0016197 IDA acts_upstream_of_or_within endosomal transport 11563910 Process
9525 GO:0032510 IMP involved_in endosome to lysosome transport via multivesicular body sorting pathway 15024011 Process
9525 GO:0033993 IDA involved_in response to lipid 16757520 Process
9525 GO:0039702 IGI involved_in viral budding via host ESCRT complex 24107264 Process
9525 GO:0043162 IMP involved_in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 22547407 Process
9525 GO:0046761 IMP involved_in viral budding from plasma membrane 14505570,16193069,17940959 Process
9525 GO:0051261 IDA involved_in protein depolymerization 18687924 Process
9525 GO:0061952 IMP involved_in midbody abscission 20616062 Process
9525 GO:0090611 IMP involved_in ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway 22547407 Process
9525 GO:1901673 IMP involved_in regulation of mitotic spindle assembly 20616062 Process
9525 GO:1903542 IMP involved_in negative regulation of exosomal secretion 24105262 Process
9525 GO:1903543 IMP involved_in positive regulation of exosomal secretion 22660413 Process
9525 GO:1903724 IMP involved_in positive regulation of centriole elongation 20616062 Process
9525 GO:1904903 IDA involved_in ESCRT III complex disassembly 18687924 Process